A/B testing

Aim 2. Toxicity testing. In these experiments we aim to establish the maximum tolerated dose (MTD) of each drug, using the recommended dosing schedule. We will measure weight gain/loss and will assess toxicity through additional parameters (e.g. haematology analysis). Aim 3. Efficacy testing. In these experiments we will measure the effects of drugs on the progression of the leukaemia, measured as the proportion of human leukaemic cells in the peripheral blood. We will do this either as a…

Abstract— improving performance of software, sites and services is a holy grail of software industry. A new approach for implementation of Poka-Yoke method in software performance engineering is proposed. Poka-Yoke is a mistake proofing technique used in product design. The effectiveness of Poka-Yoke in software development was evaluated using two case studies: product redesign mini-project given to six groups of students and a survey of online services in the software industry. Both…

There is a highly controversial argument of using animals for scientific or commercial testing. Chimpanzees have 99% of their DNA in common with humans; furthermore, mice are 98% comparable to humans on a genetic level. The United States and Gabon are the main two nations that permit experimentation with chimpanzees (ProCon.org). “95% of animals” utilized in experimentation are not “protected by the federal Animal Welfare Act (AWA), which excludes birds, rats and mice bred for research, and…

About 2 billion people have evidence of past or present infection of HBV, and 248 million of these are chronic carriers of HBV in worldwide. Most of the people currently living with HBV infection are persons that were born before hepatitis B vaccination. The Prevalence of HBV in Iran is around 2% in general populations except Sistan and Baluchestan (3.38%-5%) and Golestan (5%-7%) Provinces that is higher than other parts of Iran. It seems that with the measures of the Ministry of Health,…

I Do Have One, her humorous reflection on her life. Though Ellen DeGeneres makes a hyperbolic point, she questions the ethicality of animal testing. The practice of animal testing mutilates the physical appearance of traditional house pets, corrupting their gene pool and increasing the physical and genetic deformities for generations to come. Animal testing is superfluous, with the costs outweighing…

Hepatitis is an inflammation of the liver. There are five forms recognized they are A, B, C, D, and E. Some forms of hepatitis are sudden and brief and others can be chronic (Hepatitis). Viral hepatitis is the leading cause of liver disease in the United States and the world (Jenkins). Hepatitis is usually caused by a viral infection, but there can be other causes these include autoimmune hepatitis and hepatitis that occurs as a secondary result of medications, drugs, toxins, and alcohol.…

Hepatitis B is an inflammation of the liver, caused by the Hepatitis B virus[1], and characterized by diffuse or patchy areas of necrosis[2]. Hepatitis studies that classified the types of Hepatitis began after World War II (1945)[3] just over 70 years ago. Two decades later in 1967, Krugman studies found Hepatitis A and Hepatitis B[3]. Another ten years later, the Prince studies found the specific virus surface antigen that causes Hepatitis B[3]. Taxonomically classified in the…

pulled it apart. It read: Day one of Serpentus Albus' testing. Entry Two. Nothing has happened with Albie yet. I have tested everything so far. The beast seems to be able to think words and speak, but I am not sure. I cannot seem to get any readings on his behavior because when I go near him, usually he is either asleep, or he acts like a child. He would fold his body like a human's arms and cross them with a grumpy look on his face. This testing is proving to be a failure at the moment. I just…

Impact of a humanized rat liver model Having a rat model with a more-human like liver will allow investigators to better understand normal and diseased human liver physiology and biochemistry (82). It will allow us to test and compare the ability to repopulate livers with different cell sources which have had limited success in the mouse (3). Primary human hepatocytes have been shown to efficiently repopulate recipient livers (32), however with limited access to large quantities, researchers…

problem that has started many arguments in the world is the problem of animal testing. This is because it is related to ethics of animal life and their welfare in the laboratory system. According to the US department of Agriculture Animal (USDA) and Plant and Animal Health Inspection Service (APHIS), 834,453 animals are used for scientific and commercial experimentations in 2014 (USDA, 2). Many scientists argue that animal testing has a great impact on prolonging life for humans. Mostly,…