Senescence

The day my father died, September 4th, 2014, will always feel bitter-sweet. About a year and a half before his passing he was shot several times by police outside our house in Killeen. His body never healed up completely after this occurrence. When he died on the fourth, my immediate family gathered my siblings together and they told us about the news that evening. Despite the sadness, after being with my father and family traveling all over foreign nations, I realized how dedicated he was to…

What is cancer? Every day billions of mutations occur in human cells, but some of them make the cell cancerous. Cancer, one of the leading cause of death in the world, is a disease caused by occurring mutation in many genes of a cell, not just one gene, which changes underlying principles of the cell molecular action, such as the cell cycle, growth trend, signaling, and its specific death time.(2) The most crucial characteristic of a cancer cell is the excessive, uncontrolled growth cycle…

What is bladder cancer? Bladder cancer is a disease in which malignant cells forms in the tissues of the bladder wall. The bladder is the organ that stores urine.1 What causes bladder cancer? Scientists do not completely understand the causes of bladder cancer; however, there are some risk factors associated with its occurrence like: • Age (the risk of bladder cancer increases with age. About nine out of 10 people with bladder cancer are older than 65);2 • Smoking (smoking greatly increases the…

Cancer has a major impact on society in the United States and across America. In 2016 an estimated 1,685,210 new cases of cancer will be diagnosed in the United States and 595,690 will die from the disease. The most common cancers in 2016 are projected to be Breast Cancer, lung and bronchus cancer, prostate cancer, colon and rectum cancer, bladder cancer, melanoma of the skin, non-Hodgkin lymphoma, thyroid cancer, kidney and renal pelvis cancer, leukemia, endometrial cancer, and pancreatic…

Cancer, a disease that claims the lives of millions of individuals each year. Almost everyone in the world seems to be familiar or knows a loved one or friend with cancer these days. Cancer is so common that nearly 7.6 million people die from it around the world each year, and the number is progressively getting larger. The main question in today’s time is “Why doesn’t everyone get cancer?” Studies show that lifestyle, genetic disposition, and chance are reasons that people do get cancer.…

Introduction Before researching about the possibility of using telomerase inhibitors to kill cancer cells, we first need to know what cancer is and what telomerase is. Cancer is the name used to describe the diseases in which cell have abnormal growth or cell divides is uncontrollable and it will affect other cells. These cancer can spread to other part of the body through the blood or lymph systems. Many people think that cancer is just a disease, in fact, cancer is not just a disease but it…

Duckweeds, or water lens, are flowering aquatic plants which float on or just beneath the surface of still or slow-moving bodies of fresh water and wetlands. Duckweeds are good for experiments because they are very simple plants, lacking a stem. Duckweeds are commonly found in environments that are associated with fertile, even eutrophic conditions. Since duckweeds can provide nitrate removal and can absorb mineral nutrients such as nitrogen and phosphorus, they are known for purifying water.…

INTRODUCTION Biological ageing, or senescence, is a complex process characterised by progressive functional deterioration and cognitive decline (1). Accumulation of age related changes make individuals more prone to death and disease (2). Understanding these changes is important to understand the complexity of the human lifespan. The Hallmarks of Aging (3), is an article which describes nine factors that contribute to the ageing process. Aggravation or alleviation of these could contribute to…

Chronological lifespan of S. cerevisiae mutants lacking telomere capping protein Cdc13 and Exo1 Lay summary For over 25 years, yeast has been used as a model to understand cellular processes such as how; DNA is repaired and produced, also for understanding different aspects of the cell lifecycle and principle molecular processes in eukaryotes (the same type of cells that make up humans, animals and plants). Because yeast can be easily grown until it dies in a relatively short time, it is an…

Senescence is a metabolically active, but non-replicative state of the cell cycle, where the cells are arrested at the G0 stage and senescence has been associated with organismal aging (Nielsen, et al. 2015). Cells that continue to replicate with severely degraded telomeres may be at a higher risk damaging the coding regions…