Senescence

health trajectories. Ageing process was once described as “an unsolved problem in biology” by Medawar, but nowadays, collectively data from various sources proved that it is no longer unsolved now [1 in essay]. As Balcombe et al. described ageing and senescence as “progressive changes in the tissues or organs of the body, leading to a decline in function and death” [2 in essay]. Much researches have been carried out…

Winter cover crops on agricultural lands have been identified as an essential management practice with the potential to positively impact water quality by reducing the loss of water soluble nutrients, such as a nitrogen nitrate or NO3--N, from the soil due to rain and irrigation, which is also known as nitrogen leaching. Water quality is also positively impacted from sediment transport, or the movement of inorganic and organic particles by gravity and water. These crops serve to capture excess…

depending on many contexts including cell type, duration and severity of hypoxic exposure. The sphingolipid ceramide, similar to p53, is involved in various growth suppressive activities such as the induction of cell cycle arrest, apoptosis and senescence. Accordingly, previous findings have generated conflicting data regarding a possible link between ceramide…

Foundation. Hope has supported the SENS Foundation for several years. In fact, this very enterprising entrepreneur has given over 1 million dollars to the organization through the last several years. SENS or “Strategies for Engineered Negligible Senescence refers to the absence of aging symptoms that are attributed to certain animals. For example, the tortoise and the hydra. The Aging Factor Jason Hope was attracted to supporting anti-aging research because he would like the scientific world to…

Nuclear Transplantation Cloning Nuclear transplantation cloning is a way of reproducing when one is unwilling or unable to use gametes. A procedure can remove the nucleus from an oocyte and replace it with a nucleus from a somatic cell. Then, a stimulus will cause the egg cell to start replicating. The gestation part is the same as with anyone conceived; one will be gestated for nine months before birth. There are controversial views on cloning, with Kass strongly opposing the idea. One…

Report 1 on Martin, “The Egg and the Sperm” The phenomenon of the human reproductive process is typically understood through the main concrete reasoning, of the egg and the sperm. However we must also look for subtle cultural connotations of the main characters in this subject. The author of the article, The Egg and the Sperm: How Science Has Constructed a Romance Based on Stereotypical Male-Female Roles, Emily Martin, discerns the difference between basic scientific language and the…

frequent breaks to relieve pain. At times patient, must lie down to gain comfort from radicular pain. However intervertebral disk change with age and is known as degenerative changes relative early in life. Cell senescence in the disk has been linked with degenerative disease, with move senescence of cells in the nucleus pulpous compared to the annulus fibrous in individuals with…

One source of negative associations and attitudes towards elderly folk is due to the “biomedicalization of aging”, or the redefining of age as a medical problem rather than a natural part of life. Americans see old age as a time of senescence, decreased productivity and overall reserved capacity. “Old age” is seen as a disease in itself, attributing it as the cause for a wide range of problems. Sankar (1984) attributes this belief partly to medical professionals, who tend to utilize…

Hamilton, 2000). Many studies propose that physical activity and exercise are able to decrease the risk of undesirable consequences related with advancing aging (Myers, Prakash, Froelicher, Do, Partington, Atwood, 2002, pg. 794). Advanced aging or senescence, has been known to increase the risk of chronic conditions and diseases such as dementia. Over the recent decades, life expectancy has increased leading to an increase in age-related diseases. An increasing number of studies have found that…

1.2 Cellular DNA Damage responses, genomic instability. DNA is the blue print of life and all the information of life processes such as growth, metabolism, reproduction etc are encoded in the sequence of it. Therefore its very important to maintain the genomic integrity of this genetic material, not only to keep away defects in life processes but to pass a faithful information to the next progeny. Integrity of the DNA is usually challenged by both endogenous and exogenous agents who are capable…