Forty-two-year-old male has been diagnosed with degenerative disc disease of the lumbar spine of L4, L5, and S1 of the sacrum region. Patient also have a mild case of osteoarthritis in the sacrum region of the spine with radicular pain originating at the fifth vertebra. Patient complains of lower back pain while standing and walking which cause the patient to take frequent breaks to relieve pain. At times patient, must lie down to gain comfort from radicular pain. However intervertebral disk change with age and is known as degenerative changes relative early in life. Cell senescence in the disk has been linked with degenerative disease, with move senescence of cells in the nucleus pulpous compared to the annulus fibrous in individuals with
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Osteoarthritis has a known cause, which may be trauma infection, hemarthrosis, osteocrosis or some other condition. Osteoarthritis is present worldwide as a heterogenous group of conditions that lead to slow progression of the joint structures with integrity of articular cartilage and underlying bone. Osteoarthritis can lead to deformity and loss of function the underlying problem in this case is osteoarthritis, even though the diagnosis only says that the osteoarthritis is in the sacrum region of the spine both conditions are linked together however. During the stages of healing patient still may be at a level of discomfort, but however the body is still working to heal itself …show more content…
The fibroblasts proliferate and synthesize and secrete proteins such as types of collagen during the phase of healing Hemostasis and degeneration. The function of these proteins is to reconstruct the extracellular matrix and provide a scaffolding- like framework for the developing endothelial and parenchymal cell. It is a t the point that this proliferation and migrations occurs as epidermal skin cells in the top layer move down the sides of the wound to help fill the gap. Fibroblast move in from the dermis, and new blood vessels from to create granulation tissue, which later becomes scar tissue. The next phase of remodeling eventually progresses into the final maturation phase of remodeling eventually progresses into the final maturation phase as the regenerated tissue reorganizes into healthy scar tissue. Inflammation serves as a vital role in the healing process. Inflammation has both protective and curative features. Every step serves a specific purpose and is necessary as the body responds to tissue injury or damage. The goal of the inflammatory process is to replace injured tissue with healthy regenerated tissue, a fibrous scar, or both. The functions of the inflammatory reaction are to inactivate the injurious agent, to break down and remove the dead cells and to initiate the healing tissue. The key components are
Osteoarthritis has a known cause, which may be trauma infection, hemarthrosis, osteocrosis or some other condition. Osteoarthritis is present worldwide as a heterogenous group of conditions that lead to slow progression of the joint structures with integrity of articular cartilage and underlying bone. Osteoarthritis can lead to deformity and loss of function the underlying problem in this case is osteoarthritis, even though the diagnosis only says that the osteoarthritis is in the sacrum region of the spine both conditions are linked together however. During the stages of healing patient still may be at a level of discomfort, but however the body is still working to heal itself …show more content…
The fibroblasts proliferate and synthesize and secrete proteins such as types of collagen during the phase of healing Hemostasis and degeneration. The function of these proteins is to reconstruct the extracellular matrix and provide a scaffolding- like framework for the developing endothelial and parenchymal cell. It is a t the point that this proliferation and migrations occurs as epidermal skin cells in the top layer move down the sides of the wound to help fill the gap. Fibroblast move in from the dermis, and new blood vessels from to create granulation tissue, which later becomes scar tissue. The next phase of remodeling eventually progresses into the final maturation phase of remodeling eventually progresses into the final maturation phase as the regenerated tissue reorganizes into healthy scar tissue. Inflammation serves as a vital role in the healing process. Inflammation has both protective and curative features. Every step serves a specific purpose and is necessary as the body responds to tissue injury or damage. The goal of the inflammatory process is to replace injured tissue with healthy regenerated tissue, a fibrous scar, or both. The functions of the inflammatory reaction are to inactivate the injurious agent, to break down and remove the dead cells and to initiate the healing tissue. The key components are