this sedative also caused severe birth defects to those who had taken the drug during their pregnancy. The drug was able to cross the placenta and interfere with the distribution and spread of nutrients to the baby. The drug proved itself to be a mutagen due to the fact that it commonly inserted itself into guanine sites of the new baby. This caused the DNA to be disrupted and malformations to occur (Stephens, 2000). Along with disrupting the DNA thalidomide also interfered with the production…
1. Introduction Plants are crucial to the health and wellness of humanity. Over thousands of years, in an attempt to establish themselves within a single region, early humans began to use cultivation techniques, which is now called agriculture. It was with the advent of farming - when men realized that planting seeds resulted in germination - that societies began to develop more than 12,000 years ago. Communities then started to grow plants to feed them, and over the years, they developed a…
byproducts include adult leukemia and other cancers. Sound familiar? Crude oil also has neurotoxins, or toxins that effect the brain, which in the case of crude oil, is especially harmful to developing brains. Oil exposure leads to birth defects (mutagens and endocrine disruptors) and higher rates of cancer (teratogens) and brain problems in developing children. Crude oil is a very hazardous combination of all of these toxins. “‘It's…
Gene Mutations Gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations are affected by the change in the DNA sequence. There can be many different types of mutations. (Department of Genetics, Stanford School of Medicine, Para I) Some examples are point mutations, missense mutation, nonsense mutation, frame shift mutation, silent mutation, deletion, insertion, and duplication. (US National Library of Medicine) These mutations can either occur naturally or actually…
replication will then cause the new guanine to pair with cytosine. This is a transition mutation. 18. The Ames Test is used to determine potential carcinogenic effects of chemicals. This test uses S. typhimurium that cannot synthesize histidine. Mutagens are then added that causes missense or frameshift to fix the mutation and allow it to grow. 19. MutT is important because it helps in the degradation of base 8-Oxo-dGTP (oxoG). The base oxoG is able to form pairs with C and A. Cells that lack…
Diesel Emissions and Cancer 2 Diesel engine emissions from shipping freighters is a large source of air pollution all over the world. The Great Lakes region of the United States has very high concentrations of air pollution from these toxic emissions. The air quality in this region is considered poor. Several studies have been done linking increased rates of lung cancer to these emissions. These large vessels (shipping freighters) rank second only to power plants as to the health risk…
The faculty at the University of Waterloo have strongly impacted the world with their tobacco research. By combining scientific evidence with innovative technology, they create resources to help young Canadians quit smoking.(1) The accomplishments of UW staff and students have been recognized around the world. Their innovative approaches and extensive research on smoking have received attention from the World Health Organization, the Canadian Cancer Society and the Canadian Medical…
Codenamed the “Manhattan Project,” the atomic bomb dropped on Hiroshima and Nagasaki at the end of World War 2 was the single-biggest military construction project in history (The Atomic Bombings, n.d.). Responsible for approximately 200,000 casualties, the atomic bomb left a path of total destruction and devastation in these two major Japanese cities (The Atomic Bombings, n.d.). It was the only time nuclear weapons had been used on civilization, which gave us a true idea of what the effects…
Motivation for the Bomb As the Manhattan Project drew to an end, President Harry S. Truman knew he was coming upon the most difficult decision of his life. He could drop a bomb that would vaporize thousands of lives but would end a war in Japan, or he could continue on and cause more American, Allied, and Japanese military casualties. Truman decided to use the first atomic bombs ever made, codenamed “Little Boy” and “Fat Man”, to obliterate Hiroshima and Nagasaki in an attempt to end what was…
's items, including building materials, furniture and sustenance packing materials, and cosmetics. A few substances and standard toxic substances are responsible for changes in typical cell DNA? Substances that bring about DNA mutagens that causes cancer are known as cancer-causing agents. A cancer-causing agent is any substance that can acquire development…