Gene Mutation Essay Examples

Gene Mutations
Gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations are affected by the change in the DNA sequence. There can be many different types of mutations. (Department of Genetics, Stanford School of Medicine, Para I) Some examples are point mutations, missense mutation, nonsense mutation, frame shift mutation, silent mutation, deletion, insertion, and duplication. (US National Library of Medicine) These mutations can either occur naturally or actually made to happen. Mutations can have a huge impact that can be beneficial or unhelpful. Mutations can occur in humans, animals, or plants. Mutations affect today’s society in many ways. Mutations can be caused by external (exogenous) or endogenous (native)
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This is another example of a “point mutation”. Nonsense mutation is the substitution of a single base pair of DNA that leads to the appearance of a stop codon where previously there was a codon specifying an amino acid. A codon is a sequence of DNA or RNA nucleotides. The presence of this premature stop codon results in the production of a shortened, and likely nonfunctional, protein. Ten percent of the people who have Cystic Fibrosis, have the nonsense mutation in there gene of CFTR gene. CFTR stands for Cystic Fibrosis Transmembrane Conductance Regulator. Silent mutation is also a different type of gene mutation. Silent mutation can also be called “point mutation”. Silent mutation alters the DNA sequence, but has no apparent detectable effect on a phenotype or a function. It’s called “silent” because it might seem to not have any change done to the whole sequence of codons. They change one of the letters of the codon but the amino acid remains the same. Mental disorders can be caused by this …show more content…
Over time, genetic mutations create genetic diversity, which keeps different populations healthy. If the mutation helps the organism to survive and produce offspring, it is beneficial. Mutations are context dependent, meaning their environment determines whether the outcome of the mutation is beneficial. An example of when mutations is beneficial is antibiotic resistance in bacteria. In an environment where antibiotics are present, mutations in the bacterial DNA that alter the target of the antibiotic allow the bacteria to survive and they got to past the “fit for survival

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