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  • Phase Solubility Essay

    Phase Solubility results The phase-solubility diagram (figure 1) obtained was classified as AL type(20) because the apparent solubility of ISH increased linearly with β-CD concentration over the entire concentration range studies, thereby suggesting the formation of a water soluble complex. A slope value of less than one indicated that an inclusion complex in a molar stoichiometric ratio of 1:1 was formed between the drug and β-CD in solution. The stability constant (718.58 M–1), computed from…

    Words: 1715 - Pages: 7
  • Starch Disorders: The Composition Of Wheat Starch

    Results and Discussion 3.1 Composition of wheat starch granules The composition of starches and their separated A- and B- granules of two varieties are shown in Table 1. Amylose content of starches lies between 16.96 -24.69. The B-granules of the both varieties showed the lower value of amylose content while A- granules attributed to the high amylopectin to amylose ratio. Swelling power results the ability of starch to hydrate in specific cooking and heating process (90 °C/ 30 min.). The…

    Words: 1746 - Pages: 7
  • 2.2: Preparation Of Econazole Nitrate Nannoparticles

    2.2. Methods 2.2.1. Preparation of econazole nitrate nanoparticles The econazole nanoparticles were prepared by nano-spray drying technique. Weighed amounts of econazole nitrate, carriers and stabilizers (table 1) were dissolved in ethanol (10 ml) followed by spraying through the Buchi® nano-spray dryer B-90 (Büchi Labortechnik, Switzerland). The nano-spray dryer was operated using inert loop B-295 system (Büchi Labortechnik AG, Flawil, Switzerland) operated using nitrogen gas with flow rate of…

    Words: 1534 - Pages: 7
  • Physical Activity And Well Being

    Physical activity and well being Review of literature Introduction: According to WHO physical activity is defined as moment produced by skeletal muscle that requires energy expenditure. It regulates moderate intensity, physical activity such as walking , cycling or participating in sports has significant benefits for health. It reduces the risk of CVD’s, diabetes, colon and breast cancer. According to Krause “physical activity involves bodily movement produced by the contraction of skeletal…

    Words: 1578 - Pages: 7
  • Solubility

    ABSTRACT Solubility is the phenomenon of dissolution of solid in liquid phase to give a homogenous system.Solubility is one of the important parameter to achieve desired concentration of drug in systemic circulation for pharmacological response to be shown. Poor watersolubledrugs often require high doses in order to reach therapeutic plasma concentrations after oral administration. Low aqueoussolubility is the major problem encountered with formulation development of new chemical entities. Any…

    Words: 1984 - Pages: 8
  • Cyclodextrins Research Paper

    Complexation of Cyclodextrins Cyclodextrins (CDs) are most important carriers because of their semi-natural property as it is produced from a natural material i.e. starch, by simple enzymatic conversion. Solubility and dissolution rate of BCS class II drugs can be improved by addition or by complexation with hydrophilic carriers like cyclodextrins. Cyclodextrins have the capability to form inclusion complexes with the guest molecules i.e. poorly water soluble drugs. The formed inclusion complex…

    Words: 2429 - Pages: 10
  • Salbutamol Sulphate (COPD): A Quantitative Study

    Asthma and chronic obstructive pulmonary disease (COPD) are among the most common and prevalent diseases in the world (Raadhika and Shanthi, 2012; Rao and Kulkarni , 2012). Salbutamol sulphate (SS) is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm (Sharma et al., 2015). Salbutamol sulphate is readily absorbed from the gastro intestinal tract following oral administration, and it undergoes the first pass metabolism in the liver. It requires multiple dosing a day…

    Words: 4627 - Pages: 19
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