Degenerative disease

Forty-two-year-old male has been diagnosed with degenerative disc disease of the lumbar spine of L4, L5, and S1 of the sacrum region. Patient also have a mild case of osteoarthritis in the sacrum region of the spine with radicular pain originating at the fifth vertebra. Patient complains of lower back pain while standing and walking which cause the patient to take frequent breaks to relieve pain. At times patient, must lie down to gain comfort from radicular pain. However intervertebral disk change with age and is known as degenerative changes relative early in life. Cell senescence in the disk has been linked with degenerative disease, with move senescence of cells in the nucleus pulpous compared to the annulus fibrous in individuals with…

Everyday Helga walks in the morning with her neighbor. Each day she is noticing that she has to stop sooner because her legs feel as if she ran a mile. Helga didn't think much of it until her neighbor tells her that she's walking half as fast as she usually does, but in reality she feels exhausted. How can she be walking slow? If you have this degenerative disease, weakness in your legs is the first sign. Most people do not realize they have Parkinson's because the earlier symptoms are very…

a common neurodegenerative disease that accounts for the majority of all cases of dementia (Advokat, Comaty & Julien, 2014). Although the exact cause of Alzheimer’s is unknown, it is hypothesized that two systems crucial for the communication between brain cells fail due to the down regulation of acetylcholine and the over activation of glutamate, which result in the death of neurons (IOS Press, 2008). It is believed to involve the irreversible loss of cholinergic neurons, specifically in the…

Degenerative diseases are increasingly on the rise, traditionally affecting the elderly, but in recent times, children and adults too. Often, they are either incurable or very difficult to cure resulting in many sick people with limited potential to restore them. Over the last few years, a new development has been found for those with degenerative diseases: Stem Cells. To understand how stem cells work, first we have to understand how a degenerative disease works. Most degenerative diseases are…

The development of many diseases that are located in the brain are linked to the developmental complications of aging. Amyotrophic lateral sclerosis is an uncommon disease that is known for the degeneration of motor neurons in the brain. The motor neurons that are affected control voluntary movement within the body; the degeneration of these motor neurons cause weakness throughout the body and muscles, paralysis, sclerosis and respiratory failure (Uccelli et al., 2007). Amyotrophic lateral…

Degenerative Disease One degenerative disease that is most prevalent, if not one of the most prevalent degenerative diseases among Japanese Americans, is hypertension. Hypertension, also known as high blood pressure, is no stranger to society. As a matter of fact, one in three people are affected by hypertension (Sacks,2015). When a person has high blood pressure, it puts strains on the body's organs and arteries, making them work harder than they actually have to. High blood pressure is a very…

Muscular degenerative disease is a malfunction in the body that often weakens the skeletal muscles and prevents function in the body. The disease was discovered in 1861 by a French neurologist named Guillaume Benjamin Amand Duchenne, but the discovery of the cause was founded in 1886 ("Diseases - DMD”). One particular muscular dystrophy that affects children is called Duchenne Muscular Dystrophy (DMD) in which a small percentage of boys are born with. DMD is a muscular disease that causes…

Neurologic and retinal diseases There are many different types of degenerative neurological diseases. The brain is a complex system and this makes the use of stem cells difficult to differentiate to the right cell type. The myriad connection between nerve cells and the complex interdependency with macroglia, which is made up of astrocytes, oligodendrocytes, and glial progenitor cells create a problem with creating precise structural reconstitution with stem cells. Neurological diseases including…

The effects of a concussion are so dangerous ¨They found a suicide rate of 31 deaths per 100,000 patients — three times the population norm. The mean time between a mild concussion and suicide was 5.7 years, and each additional concussion raised suicide risk.¨ The people that killed themselves over a concussion were found having CTE in their brain ¨Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease of the brain found in athletes (and others) with a history of repetitive…

The degenerative disease that I have chosen is Cirrhosis. Cirrhosis is scarring of the liver. It happens when someone has had an injury or disease for a long time that scar tissue starts to form. Is not always known what may be causing it, but there are some things that can cause it. It can be alcoholism, obesity or viruses. According to the Department of Health and Human services, cirrhosis/ chronic liver disease was one of the leading cause of death for American Indians. American Indians and…