Toxicology

here). Procedure Risk Factor Blood/Body fluid collection Volume Blood/Body fluid collection Frequency Drug treatments Local and systemic effects Drug treatments Frequency/total no. per animal Tumour/Neoplasia induction Endpoint Toxicology Substance Toxicology Volume Toxicology Endpoint/duration Anaesthesia Induction – drug, dose, route Anaesthesia Maintenance – drug, dose, route Housing Duration held D.2. for each factor identified – how to minimise adverse impact Blood collection –…

Though poisonous substances have been studied and used for thousands of years, the field of forensic toxicology, including techniques used to detect toxins in the body, experienced significant advancements in the nineteenth century. In 1814, Mathieu Orfila, considered the founder of forensic toxicology, organized poisons into six classes that were characterized by their effects, and found that toxins must somehow enter the blood in order to take effect…

preventive measure or co-treatment against biofilms in DWDS. However, limited toxicology studies that have been done on halogenated furanones formed as by-products of disinfection have reported the chemicals to be mutagenic or carcinogenic. Hence, there is a need for more toxicology studies to affirm the possible harmful effects of halogenated furanones. We propose to use zerbrafish embryos as the model organism for a toxicology…

In Europe of the animals tested, 79% are mammals, with rodent, and here mainly mice and rats, making up for 75% of total animals; another 2.6% are rabbits. Only for toxicology and safety evaluation, about 970,000 animals were used in 2005, with an 8% total. The largest share of animals required for toxicology and safety testing of 42% was used for acute and subacute toxicity testing. A second large fraction of 17.7% was used for testing carcinogenicity, mutagenicity, and toxicity to reproduction…

of these substances and the rising use of illegal networks making the need for more information about the dangers that may cause of synthetic cathinones.[3] For the these reasons, the forensic toxicology community faces a difficult…

The drawback to this is that it does not specify the exact type of drug. This can often times be determined through a toxicology test. A toxicology test cannot say for certain that someone was impaired at a specific time but the DRE can testify to the impairment level at the time of contact. Another strength is that the evaluation done by a DRE can assist in determining one or more…

Animal Testing for Medical Research Animal testing for medical research is conducted all throughout the world. It helps scientists discover new drugs, vaccinations, and cures for a multitude of diseases. These diseases included, lung cancer, heart disease, strokes, HIV/AIDS, diabetes, hepatitis C, Parkinson’s disease and several others. (Americans for Medical Process) However, discovering these drugs and cures did not transpire without a cost. While these revelations may have saved…

Radon gas became an apparent cause of lung cancer in the late 1800’s when nearly 80% of all miners were dying from lung cancer. Particular parts of mines were known as “death pits”, where all workers got sick from the high amounts of radon gas (“Toxicology Sciences”). Exposure to asbestos fibers, hair-like crystals found in rock, is considered a risk factor for lung cancer, and they are often inhaled in jobs such as shipbuilding, mining, insulation, or automotive brake repair. Studies have shown…

My primary interest of study lies in the field of forensic anthropology, in which I will analyze human remains while using a variety of techniques based on forensic chemistry to solve criminal cases. Moreover, forensic chemistry is a field of study that inspires my passion for science, while readying me for a future career as a forensic anthropologist. Ultimately, being an attendant at the Summer Pre-College Forensic Chemistry program at UMass Amherst will allow me to study a field that…

Whitney Houston was born August 9, 1963 in Newark, New Jersey. Whitney was an American actress. Whitney was also a singer who went from gospel to pop stardom. Houston started off singing when she was 15 with her mother while trying to get a record deal of her own. At age 19 she was discovered in a nightclub by Clive Davis. Houston passed away February 11, 2012 at a suite in Beverly Hills, California. Whitney was found death by her assistant that afternoon. The assistant found Whitney face down…