Thalassemia

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  • Iron Overload In Thalassemia

    Thalassemia is known to be an inherited genetic blood disorder that results in mild to severe anemia due to the abnormal formation of hemoglobin. Thalassemia is inherited by either one or both parents. A mutation in either chromosome 11 (Deisserot et al, 1978) effect the synthesis of beta hemoglobin, whereas a mutation on chromosome 16 affect the synthesis of alpha hemoglobin(Deisserot et al, 1977). Hemoglobin is a tetramer made of two alpha chains and two beta chains (Cao et al, 2010). The location of the mutation in the hemoglobin chains is what characterizes the severity and type of thalassemia. Geographically thalassemia is commonly found in places like south-east asia and china (Charoenphandhu et al, 2011). There are two types of thalassemia,…

    Words: 1615 - Pages: 7
  • An Essay On Thalassemia In Children

    the disease known as thalassemia, and while there may only be 200,000 cases of thalassemia per year in the United States, the disease is much more prevalent in the Eastern side of the world. There are several types of thalassemia, and the disease is also known as Cooley’s anemia or Mediterranean anemia. The disease is autosomal recessive, meaning that if both parents are unknowing carriers of thalassemia, there is a one in four chance of their children having the disease. Patients who have…

    Words: 1651 - Pages: 7
  • Hemoglobinopathy Case Study

    red blood cells. Example of the disease is alpha-thalassemia. This happens due to lack of one or two series of alpha-Zhlobin or beta (where the shortfall in one or two Zhlobin beta), for example, inheritance thalassemia is inherited through a recessive trait autosomal recessive physical. There are differences between the alpha thalassemia and beta thalassemia. Alpha symptoms are usually immediately after birth no need time for the appearance of the period and the second is that the alpha chain…

    Words: 1503 - Pages: 7
  • Speech On Sickle Cell Disease

    parasite that infects red blood cells (“Sickle Cell Disease: Learn.Genetics”). This also reduces the amount of parasites that attack and infect the susceptible host, giving them more protection than others (“Sickle Cell Disease: Learn.Genetics”). That is the only case in which any type of sickle cell disease or trait is beneficial to the sufferers. The types of sickle cell disease differ greatly because of the protein Hemoglobin. The first type of sickle cell disease is Sickle Beta Thalassemia,…

    Words: 1802 - Pages: 7
  • Microcytic Anemia Case Study Essay

    classifications of anemia are, microcytic, macrocytic, normocytic, and hemolytic anemia. (Buttarro, Trybulski, Polgar Bailey, Sanberg-Cook 2013). The purpose of this discussion is to review microcytic anemia, which could be the cause of the decreased hemoglobin level in case study two. Differential diagnosis: Iron deficiency anemia (IDA): IDA is a common nutritional deficiency anemia found in women of reproductive age, and older adults due to gastrointestinal blood loss or menorrhagia…

    Words: 783 - Pages: 4
  • Sickle Cell Disease (SCD)

    It happens when you acquire copies of the hemoglobin S quality from both parents. This structure of hemoglobin known, as Hb SS. Hemoglobin SC disease is the second most usual kind of sickle cell disease. It happens when you recieve the Hb C quality from one parents and the Hb S gene from the other. People with Hb SC have comparable side effects to people with Hb SS. Be that as it may, the anemia is less serious. Hemoglobin SB+ (Beta) thalassemia influences beta globin gene making. The red blood…

    Words: 1058 - Pages: 4
  • Chemical Structure Of Haemoglobin

    normal shape, red blood cells are round with narrow centres similar to a doughnut without a pickle in the centre. The cells are cave in on both sides so each one has a thin centre and thicker edge. This shape allows the cells to be flexible so that they can move through large and small blood vessels to deliver oxygen. Cells in tissues need regular delivery of oxygen to function comfortably. Irregular haemoglobin structure can, however, disturb the shape of red blood cells and disrupt their…

    Words: 767 - Pages: 4
  • Bone Grow Transplant Essay

    The underlying diseases leading to the transplant include thalassemia and various forms of leukemia, categorized into five classes of acute lymphoblastic leukemia (ALL), acute myeloge nous leukemia (AML), chronic myelogenous leukemia (CML), plasma cell leukemia (PCL), or others. The pretransplant attributes consist of categorical variables, ordinal variables, and calendar dates. The named categorical variables are derived from records and measurements and include the patient’s gender and blood…

    Words: 1042 - Pages: 5
  • Sickle Cell Anemia Papers

    sickle cell disease may experience a few complications, or have a pattern of ongoing problems that make their life shorter than living perfectly healthy. The most common and serious complications of sickle cell disease are anemia, pain, fatigue, and organ failure The cause of Sickle Cell Anemia is an inherited abnormal hemoglobin. When red blood cells are not fully developed it is called a sickle cell. When having a sickle cell it can cause swelling, deformities, yellowing at the eyes, and many…

    Words: 1399 - Pages: 6
  • Questions On Dr. Sharon Moalem's 'Survival Of The Sickest'

    Malaria is caused by mosquitoes that live in humid swamps. The thrive there and infect those that lived around the area. Humans were able to evolve to have a larger resistance to malaria. Haldane suggested that having the genetic tendency for sickle-cell anemia or thalassemia would make the chance of being infected by malaria, rarer. He was correct. But another trait was responsible for protection against malaria, G6PD deficiency. The mutation allows for more resistance. The environment was…

    Words: 1576 - Pages: 7
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