Thalassemia

A 13-year-old male is brought to his pediatrician for evaluation. The parents are concerned after the patient’s swim coach noticed that the patient’s chest “does not look normal.” Upon questioning, the patient has no particular complaints. However, during a review of systems, he admits to some recent blurring of his vision, requiring him to sit in the front of his classes. On exam, he is noted to have a tall stature with long limbs. He is able to hyperextend the elbows and can flex his fingers…

To prioritize laboratory testing in babies with the sickle cell disease, doctors should be the ones who should decide on testing algorithms by analyzing new ways to cure the disease such as gene therapy and stem cell treatments. Sickle cell is a genetic disease of the blood. It is passed down through mutated genes from each of the parents and both usually do not have the disease and are just carriers. An abnormal type of hemoglobin S, which misshapes the red blood cell, causes the disease. The…

no excuse for doctors to only screen or test based on perceived ethnicity. For example, in a study on prenatal screening for hemoglobinopathies, at least 7% of the subjects with sickle cell trait were not black, and 22% of individuals with beta-thalassemia trait were not Mediterranean, black or Asian (Bowman 2000, p 208). There is no reason to not screen all patients – while it may cost more money, it saves lives. As the medical field continues to move forward, they can hopefully move away from…

With blood smear analysis they were able to see that the mice studied showed the same effects expected to see in thalassemic patients. Red blood cell count, hemoglobin, hematocrit, red cell distribution had all decreased significantly were as reticulocytes, which are immature red blood cells without a nucleus in thalassemic mice when compared to the wild type. Using dual energy x-ray absorptiometry, they found that in the trabecular sites such as the femoral metaphysis, tibial metaphysis, and…

Disease. These are caused by mutations in a single gene, so if you could fix that gene, the baby would be born healthy. Chinese researchers stated they had used CRISPR to modify human embryos in order to cure a fatal blood disorder known as beta thalassemia. The embryos could not survive to birth, but it could be a glance of what's to come. Gene editing already has to undergo rigorous safety testing before it can be used in humans. The Nuremburg code is a set of research ethics guidelines…

mosquitoes that live in humid swamps. The thrive there and infect those that lived around the area. Humans were able to evolve to have a larger resistance to malaria. Haldane suggested that having the genetic tendency for sickle-cell anemia or thalassemia would make the chance of being infected by malaria, rarer. He was correct. But another trait was responsible for protection against malaria, G6PD deficiency. The mutation allows for more resistance. The environment was changing, becoming more…

Iron Deficiency Anemia Anemia is caused by a low level of red blood cell in the body. Some of the different types of anemia include: iron deficiency, vitamin, sickle cells anemia and thalassemia. The purpose of this paper is to evaluate the data presented to determine what type of anemia Ms. A. has. Subjective Data Ms. A is a 26-year old Caucasian woman. Who was taken to the emergency clinic by her golf partner after she started complaining of light headedness, difficulty breathing and lack…

situation either, he currently shared a room with Ruby who is Chloe's (Jayson's partner) daughter. This means that Liam-Jay was often living in very cramped conditions which may have a profound impact on his anxiety levels. Liam-Jay also has beta thalassemia trait the same as his mother Samantha Hayes. Liam-Jay has been prescribed iron medication for…

There are over a thousand genetic diseases around the world, and Sickle Cell Disease (SCD) is one of those thousand. SCD affects seventy thousand to eighty thousand Americans. “Estimated one in five hundred African Americans and one in one thousand to one thousand four hundred Hispanic Americans have inherited SCD,” (Sickle Cell Disease.) Sickle Cell Disease is inherited by the parents, has symptoms, affects the body, and can be treated. “SCD is inherited in autosomal recessive,” (Single Gene…

Today’s society consist of many diverse populations. Our nation is full of people from all sorts of ethnic backgrounds. The government conducts a survey of the census and provides information regarding the diversity of the nation. However, some individuals are lumped into a category and their culture is misrepresented. How would you feel about being called an African American when you are Jamaican? Would you lose some form of identity? Let us begin by exploring an assessment conducted on…