Melanotan 1 (melanotan) Melanotan I is a synthetic polypeptide which is an analogue of the natural peptide hormone, Apha-MSH (Alpha-Melanocyte stimulating hormone) which naturally occurs within the human body and plays the role of triggering melanogenesis. Melanogenesis is the process by which peptides lead to pigmentation of the skin, hair and eyes, and leads to the tanning process hence it is very essential in the protection of the skin against the harmful UV (ultra violet) radiation which cause skin cancer. Alpha-MSH triggers specific melanocortin receptors (melanocytes) during its mechanism of action leading to production of melanin and also causes effects on lipid metabolism, sexual libido, and appetite through the same melanocortin receptors. Melanin is the skin pigment which offers protection against the destruction of the cells by DNA. Note that skin cancer is initiated by DNA damage.…
practicable systematic screening test with high sensitivity in order to reduce the missing cases of CH specialy in preterm infants. Evidently pre-term and low birth weight infants require special cares and follow ups.10,11.In this review we try to sytematiclly review previous works in this field and provide a comprehensive protocol for screening of these high risk neonates. Up to this date, a few approaches have been introduced in order to reach this goal. One is reducing cutoff value in order…
CONCLUSION Vitiligo is a collective, acquired, discoloration of the skin, categorized by well-circumscribed ivory or chalky white macules which are flush to the skin surface. Vitiligo affects at least 1% of the total population. Although the disease does not produce direct physical weakening, it may substantially makes an impact on the psychological well-being of the patients. Appearance of skin can condition an individual’s self-image, and any pathological modification can have…
Shaina Willenberg 2/16/16 Research Paper Vitiligo Vitiligo is an autoimmune skin disease that affects a person in which they’re having the destruction of melanin in their body. This will lead to the loss of pigmentation. The loss of pigmentation in the skin is due to the melanocytes (melanin) which forms white patches on the skin. This disease can affect 1 in every 100 people in the Unites States (2). This skin disorder can affect both males and females of any race. We have a few…
for change on her dieting skills, together they begin to take early morning walks into the park. Mary Jane teaches Niecey how to cook healthy foods, she challenges Niecey to drink more daily water, though Niecey hates the taste of water. The stress from her personal life relates to her job at Primetime. Continuously, Mary Jane deal with the fact of her boss giving Meanwhile, at Mary Janes job. Mary Jane discusses the Morning topic of Motherhood and freezing eggs on that same day. She fulfilled…
progesterone resulting from LH action in rabbit. Also the same system renders some evidence for the involvement of this enzyme along with other factors in the process of implantation. Key Words: Reproductive tract, Peroxidase-Ascorbate system Pregnancy & Implantation Introduction: It has been reported that the LH in various species of animals stimulates progesterone biosynthesis or secretion by the luteal tissue or the luteinized ovary (Savard et al., 1965; Amstrong, 1968). Injection of LH…
array of hormones once it receives signals from the hypothalamus. These hormones are responsible for regulating the activities of the other glands, such as prolactin, which is involved in milk production, adrenocorticotropic hormone which responds to stress through a stimulation of the epinephrine, hormone responsible for the stimulation of thyroid, as well as the luteinizing hormone, which regulates ovulation timing and promotes sperm and egg development, follicle-stimulating hormone and sex…
If Ellie’s thyroid is hyperactive, it is releasing a large amount of thyroid hormone, meaning a large amount of T3 and T4. A large amount of T3 would greatly inhibit the release of TSH by the pituitary gland. This may appear paradoxical, as TSH stimulates the release of thyroid hormones, but in cases of hyperthyroidism, the excessive amounts of T3 and T4 are generally not caused by elevated levels of TSH. This is, unless, the aforementioned negative feedback between TSH and T3 is disrupted,…
Diganostic criteria for hypothyroidism is based on symptoms and the results of blood tests that measure the level of TSH and the level of the thyroid hormone thyroxine. The high level of TSH and low level of thyroid hormones as known as free T4 level indicate an underactive thyroid hormone or hypothyroidism. When the thyroxine level is low, the pituitary gland produces TSH to stimulate thyroid gland to produce more thyroid hormone. TSH tests play an important role in managing hypothyroidism.…
Hypothyroidism Hypothyroidism, also known as an underactive thyroid, refers to a lack of thyroid hormone produced by the thyroid gland. Thyroid hormone affects the activity of almost every organ and tissue in the body. The thyroid gland, located in the medial, inferior portion of the cervical region, lateral and ventral to the trachea, helps to regulate the body’s metabolism, heart rate, and energy levels (“Hypothyroidism (Underactive Thyroid)”, WebMD 1). Approximately 20 million Americans…