Genetic linkage

understand the disease, investigations were done to identify the gene that is linked with the disease. Some of the common approaches to do this was linkage analysis and positional cloning often involving the use of polymorphic DNA markers to identify the best candidate gene that can…

Gamble My mind was a crystal vase that contained only one desire, which was to win. I slumped back into my red leather chair, as the Slots machine again stole my money, it was my sixth loss in a row. The big flashing red words of “LOSS” on the digital screen and the loud voices of joy fed on my insecurities. I was sitting here bleary-eyed and unshaven in front of this wealthy machine, but I was only adding to its wealth, as I slowly munched through the family’s life savings. I just spent 2 hours…

Color Blindness is defined as the inability or decreased ability to see color, or perceive color differences, under normal lighting conditions. Color blindness is also referred to as color vision deficiency. In the United States alone there are about three million cases noted per year for color blindness. This disorder seems to affect men more than it does women. It is estimated that around eight percent of males and a little less than one percent of females are diagnosed in the United…

Discussion: My first hypothesis that the sepia eye and ebony body experimental cross would result in a 9:3:3:1 ratio, and that the traits would be autosomal, unlinked recessive, was found to be false. I chose to reject my hypothesis because my calculated test statistic, 587.5, was larger than the critical value, 7.815. The traits, ebony and sepia, are linked, seeing that they fit in 2:1:1 linkage ratio and that the recombinant number is smaller (Table 1.1). They are autosomal; the amount of…

Ectodermal Dysplasia Jonathan Moon American Fork Junior High A2 2/24/17 Abstract Ectodermal Dysplasia is a group of conditions that interfere with the normal functions of skin, hair, nails, teeth or sweat glands. These abnormalities cause various issues with everyday activities such as eating, brushing hair, exercising, and blinking. This paper will explain how this disease occurs, its symptoms, diagnosis, and treatment. Causes of ED Ectodermal Dysplasia, or ED, is a genetic disorder that…

Evolving our Genetic Ideas Evolution was a recognized theory long before heredity was properly understood, however, Darwin has allowed us to understand human evolution to a far greater extent than he would have ever imagined. Genetics can be expressed in many different ways. The more often a specific phenotype is observed within the population may relate to how favourable that phenotype is for survival. This is because of relative frequency and lethality. Relative frequency is the number of…

Drosophila Melanogaster, or better known as the common fruit fly, is found all over the world and referred to as the cosmopolitan species (Mitrick, 2010). This fruit fly has three main body parts, which include the head, the thorax, and the abdomen. On males, the bottom half of the abdomen is black, while on the female, each segment of the abdomen is striped black. Drosophila have four main stages to their life cycle. These include: egg, larva, pupa and adult. The eggs small and translucent eggs…

Introduction Fruit fly Drosophila melanogaster that is used as a model to study genetics for more than a hundred years. Thomas Hunt Morgan, in the early 1900’s, used the heritable traits of a common species of fruit fly to develop our understanding of genetics. Morgan was the first to show through experiments that genes were located on chromosomes. He also found that certain fruit fly traits like eye color are found on the same chromosomes that also determine their sex. Fruit flies have several…

identify 29 promising candidate genes with supposed physical linkage to homologous Brassica genome regions involved in seed weight. Our results suggest the following 9014 homologous genes were mapped in the CIs of 47 QTLs. A large number of important genes were found to be candidate genes for seed weight. It is interesting to notice that some genes showing major effects on seed size/weight in Arabidopsis, such as ISE2/EMB25, MINI3, IKU1, IKU2, TTG2 and KLU. For example KLU expression in a growth…

I would like to be genotyped to see if I am a carrier for certain alleles for Transcription Factor 7-Like 2 (TF7L2) gene and if my family is genetically susceptible to the diseases. In other words, I want to know which SNP and what genotype I hold. The reason behind my decision is that I know that T2D is caused by environment and genetics. Getting tested will help me take further actions if my results show that I have predisposition. Many factors contribute to type 2 diabetes,…