Genetic linkage

Mitochondrial is the inheritance of a trait converted into mitochondrial genome. https://www.medicinenet.com/script/main/art.asp?articlekey=4402 The mitochondrial inheritance is caused by mutations in the mitochondrial DNA that is maternally inherited from the mother. The Mitochondria is structure of organelles, that is found in the cells located in the cytoplasm outside the nucleus. The mitochondria job is to manufacture energy in each of the cells and throughout the body…

For many decades, linkage analysis has been well-established and shown to be an effective tool for studying the complex quantitative traits. Despite of its great successes, this approach has great weakness because it only captures limited allelic diversity existing in two parental lines and also limited in low genomic resolution (Borevitz and Nordborg 2003). To address this issue, GWAS utilizing diverse germplasm collections and recombination events that have been accumulated during the…

in which our genetic material is carried on from one generation to the next. Nucleotides join together through phosphodiester linkages between the 5 ' and 3 ' carbon atoms to form nucleic acids. “Nucleotides are composed of a five-membered sugar group with a purine or pyrimidine nitrogen base group attached to its 1 ' carbon via a glycosidic bond and one or more phosphate groups attached to its 5 ' carbon via an ester bond” (sparknotes.com/biology). DNA and RNA both contain genetic information,…

Chapters 1 to 10 Overview A History of Genetics by A.H. Sturtevant provides a brief history of work prior to Mendel and the author’s firsthand account of the events and research that helped shape the field of genetics. Early on, various hypotheses were beginning to be formulated by scientists such as Aristotle, Hippocrates, and Darwin. These include pangenesis, hybridization, and human inheritance which provided Mendel with some ideas to develop his own understanding of heredity. Also, the…

Reserve genetics is a tool used to identify the functionality of a known gene sequence or a gene family by genetic editing to generate the mutant phenotype. As it is done in a direction from gene to phenotype, which is opposite to ‘forward genetics’, hence named as reverse genetics. As the whole genome sequences are much more accessible nowadays with various genome sequencing technologies developed. This enables modifying a known gene, and to create a known mutation. The mutated gene might then…

Gregor Mendel was born into an ethnic German family his name was originally Johann but was given the name Gregor when he joined the Augustan friars He was the son of Anton and Rosine Mendel. He had two siblings, his older sister veronica, and a younger sister named Theresia. He grew up on a farm that his family had owned for at least 130 years. When he was little he worked as a gardener and studied beekeeping. When grew older he attended gymnasium (a type of school with a strong emphasis on…

Drosophila melanogaster the concept to understanding genetic inheritances from Parental to Offspring Lab Three: Genetic Experiments with Drosophila Arizona State University Kira James Professor Hoffman LSC 348: Fundamental of Genetics Lab Monday 27 October 2014 Abstract Drosophila melanogaster is a small, common fly found near upripe and rotted fruit. It is one of the most valuable organisms in genetics research since they are practical, small and have a short life cycle of about two weeks…

The experience one can get while matching the definite laminopathy symptoms with the mutations revealed in the patients LMNA gene, in any case, bring us closer to understanding the genetic basis of…

how much genetic variance can account for the variations of cognition that are observed in the human population (Plomin et al, 2013). Over the years, we have in some ways learned an immense amount about intelligence, yet when reading even the most recent reports it appears that we know hardly anything at all. One thing that most scientists can agree upon, is that fact that intelligence is a polygenic…

melanogaster is important since it is a widely-used model organism in genetics research. It is important to understand which genes and alleles are present in which chromosomes, what the function and phenotype of the corresponding gene is, and if multiple genes are significantly linked and do not separate independently during…