Amyloidosis

Amyloidosis is an incurable fatal disease where abnormal proteins called amyloid fibrils are misfolded and then deposited in the tissues and organs of the body. It is a serious condition that can affect one organ or tissue or multiple organs at the same time. This study was performed to analyze and describe the latest clinical trials, research, diagnosis procedures, treatment plans, and drugs available for the treatment of amyloidosis AL (primary), AA (secondary), ATTR (hereditary and senile), and Localized. The findings show that middle age and elderly, males more than females, are at higher risk to develop this disease. The study suggests the importance of diagnosing the disease in an early stage and accurately in order to treat it satisfactorily…

The disease that was chosen for me this time was Amyloidosis. The cause of this disease on your body is there is a buildup of amyloid (abnormal protein that is usually produced in your bone marrow and then can go to any organ or tissue) in your organs. This disease is classified as pretty rare and incurable. There are a variety of characteristics that show up depending on what part of your body the disease is affecting. Symptoms show up when the disease has advanced. Some of these include severe…

still unknown what causes these fibrils to form, however scientists know that the folds are found in the light chains, also known as the Lambda chains. This specific immunoglobulinic amyloidosis is also referred to as AL or “primary” amyloidosis. AL amyloidosis is considered to be the most common type of systemic amyloidosis in western countries. AL amyloidosis is usually a systemic disease, characterized by these fibril proteins depositing into multiple organs. Renal manifestations are the…

There is no specific treatment for primary restrictive cardiomyopathy; the main goal is to treat the heart failure symptoms caused by restrictive cardiomyopathy. With secondary types of restrictive cardiomyopathy like amyloidosis and sarcoidosis however, the underlying diseases can be treated. The backbone treatments for restrictive cardiomyopathy include diuretics, vasodilators, ACE inhibitors and anticoagulation therapies. Beta blockers help to improve ventricular relaxation and diastolic…

Patients with high blood pressure can get hypertrophic cardiomyopathy because the heart has to pump blood harder because of the high pressure within the blood vessel. Over time, the heart muscles thicken and making it increasingly harder for the heart to pump an adequate amount of blood. WIth age someone can get hypertrophic cardiomyopathy or restrictive cardiomyopathy. However, restrictive cardiomyopathy occurs when there is a buildup of scar tissue that appears after having heart surgery.…

"Here at home, the war has not ended for many of the 2.8 million serviceman and women who went to Vietnam. In addition, Vietnam claims half a million children have been born with serious birth defects, while as many as 2 million people are suffering from cancer or other illness." The U.S. used Agent Orange as a strategy to open up the Vietnam jungle so tanks and APC's could take part in operations. When the U.S. sprayed Agent Orange, they didn't realize how much it would effect U.S. soldiers,…

establish amnestic MCI []. According to more recent literature, the clinical criteria for amnestic MCI include: [13,14]. 1. Memory complaint, usually corroborated by an informant 2. Objective memory impairment for age 3. Essentially preserved general cognitive function 4. Largely intact functional activities 5. Not demented In addition to the clinical criteria, the use of biomarkers increases the certainty of whether or not an MCI patient will convert to AD dementia over time []. In 2011, the…

condition usually occurs when something disrupts the body's normal course of counteracting low blood pressure. This condition is common in people over the age of 65. Dehydration causes orthostatic hypotension by your body losing blood volume. Some heart conditions such as bradycardia, heart valve problems, heart attack, and heart failure can cause this condition by preventing the body from responding fast enough for the heart to pump enough blood. Some endocrine problems such as thyroid…

The many causes of nephrotic syndrome include minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, diabetic kidney disease, systemic lupus erythematosus, amyloidosis, blood clot in a kidney vein, and heart failure (Mayo Clinic, 2014b). The risk factors can include conditions that can affect the kidneys, for example, diabetes and lupus; certain medications, such as nonsteroidal anti-inflammatories; and particular infections, including HIV and hepatitis (Mayo…

life-preserving treatment. It is important for dialysis patients to understand that dialysis is not a cure for kidney disease, or any other comorbidities which may be present. End stage renal disease (ESRD) involves permanent damage to the kidneys, and dialysis is intended to help the body run as normal as possible without kidney function. If an ESRD patient does not get dialysis treatments regularly, sodium and other waste products would build up in the blood, and they would become fluid…