Telomere

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  • Importance Of Telomeres

    Introduction The field of telomere biology has been an active area of research in recent time, especially so following the work by Hayflick and Olovnikov. Expanding on his, Elizabeth Blackburn and Joseph Gall noticed that the end of the chromosomes from Tetrahymena thermophila contained the six base sequence TTGGGG iterated many times (Blackburn and Gall, 1978). Over the decades, literature has arisen that has revealed many things regarding telomeres. However, as with the case with many scientific endeavours, as one question is answered, another would arise. As a result, research in telomere biology has become one which many are deciding to take on. We know that proper replication of the telomeric DNA at chromosome ends is critical for…

    Words: 1944 - Pages: 8
  • The Importance Of Telomeres

    The diet-induced inflammation is a major reason why people gain pounds, become ill and age faster. The natural aging process happens because when cells replicate in your body, they lose a little bit of DNA from the end of each chromosome. Thus resulting in cells being different from their original cell. Many cells have a natural defense in this called Telomeres, which is unneeded DNA at the end of each chromosome, we can control how much Telomeres we have by controlling our diet and following…

    Words: 1046 - Pages: 5
  • Analysis Of Immortality By Matt Ridley

    over came many challenges. On Chromosome 14, the presence of the TEP1 gene seems to be the source of the long lived existence of life on earth. TEP1 codes for a protein that part of telomerase, which is inherently important for the immortality of cells in the human body. At the end of every chromosome, there is a section of repetitive nucleotides sequence called telomeres. The TEP1 gene codes for telomerase, an enzymes that increases the length of the telomeres after every division of the a…

    Words: 739 - Pages: 3
  • The Chronological Lifespan Of S. Ceerevisiae Mutants

    Chronological lifespan of S. cerevisiae mutants lacking telomere capping protein Cdc13 and Exo1 Lay summary For over 25 years, yeast has been used as a model to understand cellular processes such as how; DNA is repaired and produced, also for understanding different aspects of the cell lifecycle and principle molecular processes in eukaryotes (the same type of cells that make up humans, animals and plants). Because yeast can be easily grown until it dies in a relatively short time, it is an…

    Words: 2050 - Pages: 9
  • The Importance Of The 2009 Nobel Prize For Physiology And DNA

    The 2009 Nobel prize for Physiology and Medicine was awarded to Drs Elizabeth Blackburn, Jack Szostak and Carol Greider for their discovery of telomeres and telomerases; but what are they and why did the Nobel prize committee find their discovery so important? Drs ezilabeth Blackburn, Jack Szostak and Carol Greiders discovery of telomeres and telomerases can be considered as one of the key milestones in our understanding of DNA replication in eukaryotes as they helped us figure out how the…

    Words: 1758 - Pages: 8
  • Mutation In The Silencing Gene SIR4 Case Study

    silencing at HM loci, telomeres and other regions of the chromosome have been shown to relate to stress resistance and aging in Saccharomyces cerevisiae. S. cerevisiae is a species of yeast in which goes through asymmetrical cellular division. Its lifespan is measured by the number of cellular divisions the mother cell is able to complete before death. In the research study by Kennedy et al, the researchers focused on yeast cells and how stress tolerance can extend lifespan through silencing…

    Words: 821 - Pages: 4
  • Survival Of The Sickest Case Study

    The Hayflick limit works because of the telomeres. As soon as the telomeres run out, a cell is stopped. But with telomerase, cancer cells can add on to telomeres repeatedly, meaning the telomeres don’t run out. Telomeres are replenished so quickly that the Hayflick limit never has the chance to start, the cell’s DNA is protected by an everlasting set of telomeres. Scientists are working to finish a test that will immediately trace any signs of increased telomerase activity. This will lead to…

    Words: 1922 - Pages: 8
  • Effects Of Senescence

    limit of cells is primarily dependent on telomeres whose length ultimately determines the lifespan of cells (Bodnar et al., 1998; Harley et al., 1990). Additionally other inducers of senescence were also identified. Forms of senescence: Cellular senescence is essentially an irreversible state of growth arrest that is encountered by cells in response to multiple distinct stimuli. Classically, senescence is broadly categorized into two types 1) Replicative senescence and 2) Stress induced…

    Words: 969 - Pages: 4
  • Biological Immortality Essay

    Blackburn, Carol W. Greider and Jack W. Szostak for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. A telomere is a stretch of DNA which has repetitive sequences of bases at the ends of chromosomes. When scientists started to develop knowledge on how genes are replicated, they realised that on one of the double strands of DNA cannot be replicated at the very end of the strand and due to this every time a cell divides its chromosomes gets shorter but…

    Words: 1179 - Pages: 5
  • Favism In Biology

    environmental factors and factors from the mother come into play when the baby is developing inside the mother. But for females, they are born with a full set of eggs that she will have for life. So, that means that the eggs the grandchild developed from were created in its mother’s ovaries when the mother was still in her mother’s womb. This means that when the grandmother was passing epigenetic signals to the mother, these signals were also passed to you, the egg that was already formed in the…

    Words: 1960 - Pages: 8
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