Telomerase

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    The 2009 Nobel prize for Physiology and Medicine was awarded to Drs Elizabeth Blackburn, Jack Szostak and Carol Greider for their discovery of telomeres and telomerases; but what are they and why did the Nobel prize committee find their discovery so important? Drs ezilabeth Blackburn, Jack Szostak and Carol Greiders discovery of telomeres and telomerases can be considered as one of the key milestones in our understanding of DNA replication in eukaryotes as they helped us figure out how the ends of linear chromosomes are replicated. There discovery of telomeres and telomerase did not only fil A DNA molecule is made up of two strands of polynucleotides which can be described as anti-parallel meaning one strand is moving from a 3’ to 5’ direction…

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    Dyskeratosis Congenita

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    however(Dokal et al., 2011; Khincha et al., 2014). Hematopoietic stem cell transplantation can cure or ameliorate some of the blood abnormalities caused by DKC, especially in patients with bone marrow failure. However, this treatment will not affect the tissue damage caused by DKC(Sakaguchi et al., 2013). Additionally, fatal pulmonary complications as a result of this transplantation are common. Patients with DKC have a higher sensitivity towards radiation and chemotherapy drugs so treatment of…

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    Essay On Senescence

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    Senescence is a robust tumor suppressive mechanism that inhibits the proliferation of damaged as well as initiated cells in response to a diverse range of stresses. The observations that human benign cancer precursor lesions are comprised of senescent cells further provide evidence that senescence is a physiological mechanism that prevents cancer progression in humans, possibly at an early stage. Senescence is clearly not fail-safe, since cells in pre-cursor lesions occasionally progress towards…

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    is to reproduce but to get to that we have over came many challenges. On Chromosome 14, the presence of the TEP1 gene seems to be the source of the long lived existence of life on earth. TEP1 codes for a protein that part of telomerase, which is inherently important for the immortality of cells in the human body. At the end of every chromosome, there is a section of repetitive nucleotides sequence called telomeres. The TEP1…

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    professor. Her family moved from San Diego to Davis California. Carol is dyslexic and states that her compensatory skills also played a role in her success as a scientist because one has to intuit many different things that are going on the same time and imply those to a particular problem. Body Paragraph 2: This paragraph will describe what the major discoveries they made including what they discovered about cells. Carol W. Grieder had been the first one to discover a scientific enzyme which…

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    Carol W.Greider is a biologist who discovered something very important. When she completed her Ph.D. from the university of Cal Berkeley She then went of into researching of the cell. She then saw a thing called a telomerase that can cause cancer if destroyed. She was researching in Long Island, New York when she discovered a protein that stops telomerase from disintegrating. She then got the nobel peace prize for discovering that in the year 2009. Carol Greider was born in San Diego she then…

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    Greider discovered how chromosomes are protected by telomeres and enzyme telomerase. Telomerase is the ends of the chromosome. She and one other scientist determined that it was the enzyme that was responsible for telomerase addition. Telomerase is also the key enzyme in cancer and anemia research. Her discovery of these things are very important in cell…

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    treating this neurological disorder is the used of telomerase proteins, but first we must look deeper into one of the main theories to what causes Alzheimer’s to get an understanding of the disease. There are two protein abnormalities that are associated with Alzheimer’s which are Beta-Amyloid and Tau proteins (Tangles). The protein that has been most focused on in recent years is the Beta-amyloid proteins. These are cerebral plaques that are found in neocortical terminal fields.…

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    Highlands Ranch, CO, June 22, 2012 Dr. Chad Prusmack, through his nutraceutical company PruTectRx, has been authorized by T.A. Sciences to prescribe the telomerase activator, TA-65. Popularized by Suzanne Somers in her book, Bombshell: Explosive Medical Secrets that Will Redefine Aging, TA-65 has been shown to lengthen telomeres in DNA strands, which can help slow aging, hinder the development of cancer and decrease genomic instability. TA-65 is only available through authorized,…

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    Systemic Telomere

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    Systemic Telomere Length and Aging Telomeres represent essential structure for genome stability, since their role is to protect the extremities of linear chromosomes from degradation and recombination. Furthermore, they also participate in the nuclear architecture, as well as in the meiosis-specific genome recombination and reorganization. Telomere length is the result of the equilibrium between shortening and lengthening mechanisms, and in many different organisms there is a decrease in…

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