Telomere

Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae Gene mutations that affect silencing at HM loci, telomeres and other regions of the chromosome have been shown to relate to stress resistance and aging in Saccharomyces cerevisiae. S. cerevisiae is a species of yeast in which goes through asymmetrical cellular division. Its lifespan is measured by the number of cellular divisions the mother cell is able to complete before death. In the research study by Kennedy et al, the…

Soda is an addiction and all addictions have corruptive side-effects. Some side-effects of soda include irritability, restlessness, tension, insomnia, high blood pressure, gastrointestinal disturbance, excessive urination, irregular heartbeat, cell damage, dehydration, an impaired digestive system, liver problems, metabolic syndrome, accelerated aging, and cancer. Soda has toxic chemicals-brominated vegetable oil, or BVO, is an example. BVO is an industrial chemical used as a flame retardant in…

nutraceutical company PruTectRx, has been authorized by T.A. Sciences to prescribe the telomerase activator, TA-65. Popularized by Suzanne Somers in her book, Bombshell: Explosive Medical Secrets that Will Redefine Aging, TA-65 has been shown to lengthen telomeres in DNA strands, which can help slow aging, hinder the development of cancer and decrease genomic instability. TA-65 is only available through authorized, board-certified physicians. TA-65® was discovered by the biotech company…

a genotype associated with predicted long telomeres. The most extensively studied gene related to familial melanoma is cyclin-dependent…

induced in cells due to shortening of telomeres as a result of prolonged cell proliferation (discussed later), while premature senescence is induced in cells in response to cell intrinsic as well as extrinsic stresses such as oncogene activation, UV irradiation, DNA damaging agents, inadequate cell culture conditions, reactive oxygen species (ROS) amongst others. Although premature senescence induced in response to stresses was initially thought to be telomere independent, there is now evidence…

The Hayflick limit works because of the telomeres. As soon as the telomeres run out, a cell is stopped. But with telomerase, cancer cells can add on to telomeres repeatedly, meaning the telomeres don’t run out. Telomeres are replenished so quickly that the Hayflick limit never has the chance to start, the cell’s DNA is protected by an everlasting set of telomeres. Scientists are working to finish a test that will immediately trace any signs of increased…

chromosomes are protected by telomeres and the enzyme telomerase. A telomere is a stretch of DNA which has repetitive sequences of bases at the ends of chromosomes. When scientists started to develop knowledge on how genes are replicated, they realised that on one of the double strands of DNA cannot be replicated at the very end of the strand and due to this every time a cell divides its chromosomes gets shorter but telomeres explain how these codes are maintained. Telomeres serve to protect…

It was found that those who have MDD have shorter telomere length (Gotlib, I. H., Lemoult, J., Colich, N. L., Foland-ross, L. C., Hallmayer, J., Joormann, J., Wolkowitz, O. M.). Telomeres are described as nucleoprotein structures that protect the ends of our DNA and the shorter they are, the more likely a person’s DNA is to be damaged which causes one to age faster and…

In "the Average Life Expectancy Could Soon Reach Above 90 Years Old", by Maria Chang, she discusses how America is falling behind other countries on average life expectancy, despite its wealth. It is shown that countries with more money tend to have longer human life expectancies, because of their ability to afford to maintain a healthy environment. So why is the United States, the ninth richest country falling short in these ranks? "Researchers note that among rich countries, the U.S. has the…

Telomerase is an enzyme which catalyzes the addition of telomeres to the ends of chromosomes. Telomeres are repetitive non-coding segments found at the end of chromosomes with the sequence TTAGGG. Telomeres act as protective caps for the chromosomes, similar to plastic caps on the ends of shoelaces. Because DNA polymerase can only synthesize in the 5’ to 3’ direction and only adds…