Monoclonal antibodies

Darwin's evolutionary thinking has influenced many sciences, among them psychology. As one of its effects, animals began to be used in psychological research processes, and this use is justified by the assumption that the basic processes are common to different species. In these studies, the animal is used only as a means and not as the research object, with an understanding of human behavior your ultimate goal. Making a retrospective review, it is undeniable the importance of knowledge gained…

the treatment of a wide variety of ocular disease including neovascular age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vascular occlusions (RVO) [2-7]. Bevacizumab and ranibizumab , a fragment of a humanized monoclonal antibody, are the most common used anti-VEGF agents. [8-9]. In the United States, it has been estimated that over 100,000 intravitreal injections are performed monthly. This procedure might become the most common intraocular procedure worldwide…

Introduction Fed batch and perfusion batch have been used broadly in both biopharmaceuticals for years, manufacturing many different products. The choice of using one process over the other has largely boiled down to what suits a company more in terms of what is suitable to them or their preference of one process over the other. Thus when choosing these systems it is the companies long term future that is considered rather than their short term. Fed batch and perfusion batch are the 2 most…

component to Alzheimer’s disease, researchers were also able to identify what kind of future drug could help with cognitive impairment. The drug that is undergoing further research as a cure for Alzheimer’s disease is solanezumab. Solanezumab is a “monoclonal antibody designed to lower the level of beta-amyloid in the brain” (Alzheimer’s Association, 2016). If research goes well regarding this drug it could lead to a possible cure for the Alzheimer’s…

Globally individuals develop and obtain disease. Among these diseases is the hepatitis B virus (HBV) and breast cancer; two commonly spread/carried diseases, and potentially life threatening diseases. Chronic hepatitis B infection alone “is a global public health issue with >350 million hepatitis B virus carriers worldwide” (Ling, W H Y et, al,1931). Breast cancer has also been on the rise infecting not only women but men as well. So, it is not uncommon for individuals to have both…

amyloid cascade hypothesis and anti-amyloid immunotherapy. PLoS ONE, 8(3), e59735. doi:10.1371/journal.pone.0059735 The neurological changes related to Alzheimer's disease (AD) heavily support the amyloid cascade hypothesis. Bapineuzumab is a monoclonal antibody that targets the N-terminal region of amyloid-B (Aβ) peptides. Three test subjects were treated with bapineuzumab to evaluate their changes in neuropathology and biochemistry. The levels of Aβ…

Krystal Headen Professor Kaitlin Sidorsky Poli 201 1 December 2015 BLOC Cancer The breast cancer, lung cancer, ovarian cancer, and colon cancer (BLOC) interest group was formed in September 2012 as an effective organization. It began when the founder, Krystal Headen was unfortunately informed that some of her friends and family members had been diagnosed with (remove either) breast cancer, lung cancer, ovarian cancer, colon cancer, or the Kahler’s disease. Krystal spent several months building…

Chlamydia: The Silent Killer Javier Martin Waukesha County Technical College Section 11274 Instructor: Dr. Tracy Neher April 30, 2017 Chlamydia: The Silent Killer A sexually transmitted infection that affects approximately 3 million Americans per year with a yearly cost of 2.1 billion dollars for treatment and prevention is caused by the bacterial pathogen Chlamydia trachomatis. Known as the silent disease for its ability to conceal itself in the body, chlamydia…

ORGAN DONATION: THE GIFT OF LIFE Doctor’s declared that Martin Wayne Lennox would not survive three days after his birth on January 17, 1965. Having just informed his parents that their newborn son had a hole that engulfed 50 percent of his heart, the doctors said it would be a miracle if he lived. The small infant held on with what little strength he possessed and overcame the odds. Martin continued to grow and, with each doctor’s visit, his parents were told he had a very slim chance of…

Currently, Dr. Rong Lu conducts research at the University of Southern California (USC). Her lab investigates stem cell malfunction, regulation, and coordination at the single cell level (1). Furthermore, she uses mouse hematopoietic stem cells (HSCs) as a model system (1). Dr. Lu’s research utilize various disciplines of biology such as molecular, cellular, and systems biology (1). Additionally, Dr. Lu’s research focuses on investigating the differences and coordination between individual stem…