Monoclonal antibodies

• Anti-plaque formation treatment using monoclonal antibody Anti- Aβ 42 AB, such as Crenezumab, Solanzezumab and Bapinezumab. • Monoclonal Ab or gene therapy to target APOE-4 variant, treatment that mimics APP gene that confers protection against AD. • Antioxidant therapy to tackle oxidative stress. Professionals in healthcare system that…

Causes of Relapsed/Refractory Follicular Lymphoma By Liji Thomas, MD Follicular lymphoma (FL) is an indolent tumor of the lymphatic system which may often remain inactive for years before undergoing transformation into an aggressive tumor. After treatment, a high percentage of patients fail to respond, and these tumors are categorized as refractory lymphomas. Some respond with an initial positive change, but then develop signs of recurrent tumor, called relapsed follicular lymphoma. What…

The Specimen Reception – where I spent most of my day-to-day work – is part of the Lab-Med group that is situated in the Central Pathology lab, and is made up of the biochemistry laboratory, the haematology laboratory – which includes cryobiology and coagulation, the microbiology lab, the histopathology lab – which includes cytopathology, the immunology lab, cancer molecular diagnostics, and transfusion medicine, as well as the Irish mycobacterium reference lab, and the national MRSA reference…

official cure, there is many treatments to help with Lupus symptoms.Corticosteroids, including prednisone, prednisolone, methylprednisolone, and hydrocortisone are believed to help with Lupus.Along with many other medications Antimalarials , the monoclonal antibody belimumab,even Aspirin is known to help, However with all this medications it can take days ,months , and even sometimes years, for your health care team to find the right treatment to help control your lupus…

1. ABSTRACT: A total of 552 serum samples of sheep, goats and cattle from different localities at Assiut governorate, Egypt were screened for qualitative analysis of the BTV antibodies using a commercial competitive ELISA (cELISA) kit. The results showed an overall percentage of BTV positive sheep, goats and cattle serum samples were 41.86%, 24% and 85.42% respectively. A highest percentage of seropositivity was found in Arab El- Awamer farm(100%), followed by Abnoub( 63. 64%), Sedfa(11.…

Diseases exist all across the world. More importantly, a disease is a condition that impairs the body from functioning properly. Both diseases are commonly found in third world countries, due to poor water quality, sanitation, air quality, and lack of health professionals. Ebola and the Guinea Worm (Drancunculiasis) are two diseases that have made their way into the news recently. The two diseases are relatively similar, but also differ in a few different ways. There is supporting biomedical…

Figure 1. Function and Nuclear Translocation Illustration of the Nrf-2 Pathway Preliminary data showed that SUL could ameliorate hyperoxia-compromised phagocytic function. This experiment sought to explore the mechanism behind this phenomenon. We hypothesized that the activation of Nrf-2 would increase the antioxidant potential of macrophages exposed to hyperoxia by induction of antioxidant protein, HO-1, leading to a reduction in iROS and the subsequent prevention of HMGB1 release. Significant…

Pneumocystis pneumonia represents a potentially life-threatening infection caused by a fungal microorganism Pneumocystis jiroveci. Initially observed in premature and malnourished infants, Pneumocystis pneumonia is today one of the most frequent opportunistic infections in adults infected with human immunodeficiency virus (HIV). As nonspecific symptoms are often hindering timely diagnosis, one of the most important diagnostic tools for Pneumocystis pneumonia is a high level of clinical…

Introduction: LC-MS is used for the bioanalysis of small molecules drugs, which has molecular mass of less than 800 Da. Now a days, it is also frequently used for the bioanalytical determination of biopharmaceuticals.1 In pharmaceutical R & D, it takes a year to develop a new marketing drug identified from thousands of new compounds. The drug discovery is divided into early and late phase, during which pharmacokinetics study or bioanalysis of a drug is done. Once, the bioanalysis of a drug is…

Animal testing uses outdated and archaic testing procedures. In the article “Alternatives to the use of animals in research, testing and education” Jayshree Vencatesan, and advocate of Animal rights who works at Care Earth, describes how in the medical field of humane science there are three R’s every method of testing must follow. The three R’s include: replacement, refinement, and reduction. These must be used when determining alternative methods of testing. Vencatesan states that the most…