Dichloromethane

Following TLC, the sample was evaporated with the Rotavap® and then extracted using 4:1 1-butanol and ethyl acetate as the organic layer and water. The sample failed to dissolve, so the organic layer was decanted off, and dichloromethane was used instead. The bottom-layer (dichloromethane and sample) was run through the Rotavap® and the sample residue that was left was reacted with 1-pyrenehexanoic acid. The second step of forming the amide also required TLC, and was done using the same…

that used dichloromethane. Dichloromethane and another chemical called ethyl acetate were commonly use because of caffeines' polarity and solubility. Caffeine is much more soluble in dichloromethane than in water because dichloromethane is considered a polar hydrocarbon because of its structure and elements that it contains. Caffeine is very soluble in this chemical because it is also a polar hydrocarbon, while water is only polar, making it more suitable to dissolve in the dichloromethane…

that was hydrophobic since it’s nonpolar, and it essentially washed off most of the fluorene since fluorene is not as polar as 9-fluorenone. The solvent system with a mixture between Dichloromethane and petroleum ether allowed the yellow band to be eluted off the column because polar solvents such as Dichloromethane are helpful in moving chemical compounds down the column that tend to have a higher polarity, such as 9-fluorenone. Structurally, fluorene does not have a carbonyl functional group…

Extraction was the main method of removing compounds from the sample. The component X was removed from the sample by first adding the organic solvent dichloromethane to the test tube. After aggravation, the component X dissolved into the solvent. Since components Y and Z were insoluble in the organic solvent they remained as solids. The test tube was then placed into a centrifuge and ran for thirty seconds. By doing so, the unsettled solid were forced to accumulate at the bottom of the test tube…

Identifying an Unknown Compound Using Various Chemical Analysis Techniques Joshua Nash and Aquilla Young Abstract The introduction of this lab report exposes the reader to the different scientific concepts that are to be used such as melting point calculations, retention factors, and solubility in various aqueous solutions. The experimental provides the basics of using a melting point apparatus, determining solubility, and performing thin layer chromatography. In the results section the findings…

the layers have settled and two layers are visible, the separating funnel was hung on the retort stand. Next, the organic solution located at the bottom was drained off. The procedures mentioned were repeated using another 20ml of portion of dichloromethane and acquired organic extracts, mostly containing vanillin were combined. Then, poured into another clean separating funnel. Next, 40 ml of 0.1M of sodium hydroxide, NaOH solution was measured and poured into a clean 100 ml beaker. The sodium…

Thin Layer chromatography was also use to separate the mixture of fluorene and fluorenone. Thin layer chromatography is a useful separation method when the components of a mixture are in question. Analyzing what the mixture consist of can be efficiently determine by TLC by calculating Rf and comparing these values. For the separation and isolation of a mixtures components, this method is extensive and not as efficient at column chromatography. This conclusion is represented in the data gathered.…

constructed. Once the microwave was done, the vessel was rinsed with 5mL of water, which was poured into the separatory funnel. Then cold sodium hydroxide was then added portion wise to the separatory funnel and the funnel was swirled. Next, 10mL of dichloromethane was added to the separatory funnel, which was then inverted and vented toward the back of the fume hood. Once mixing was complete, the organic layer was separated into…

The goal of this experiment was to use the technique of thin layer chromatography (TLC) to identify the active analgesic ingredient of Advil and monitor the transesterification of methyl salicylate from acetylsalicylic acid. The synthesized methyl salicylate was then purified using acid-base chemistry and analyzed using H NMR spectroscopy. Identification of a proper mobile phase to separate common analgesics used in over-the-counter pain relievers was essential in being able to determine the…

The electrochemical properties of the squaraine dyes (SQ1 & SQ2) were investigated. The effects of the chemical structures of two SQ1&SQ2 dyes were selected in relation to the variable property of -COOH substituent for SQ1 compare to SQ2 which without substituent and determine their potential energy levels in ground and excited states HOMO and LUMO. The HOMO energy levels of the SQ1 & SQ2 dyes are -5.19 eV and -5.16 eV. The LUMO energy levels are calculated to be -3.08 eV and -3.1eV respectively…