TITLE: QUALITATIVE PHASE IDENTIFICATION & CRYSTAL STRUSTURE ANALYSIS OF ISONICOTINAMIDE POLYMORPHS.
The science of crystallography is important in stability studies and determination of solid state molecule or particles. Isonicotinamide (pyridine -4- carboxamide) is the amide form of isonicotinic acid which exists as different polymorphs. Isonicotinamide finds extensive use in the pharmaceutical industry because of its good anti-tubercular, anti-bacterial, anti-pyretic and fibrinolytic properties (Li et al. 2016). The crystal structure and polymorphs of Active pharmaceutical ingredients (APIs) has been found important as one of the factors that decides the effectiveness of a drug. In recent times, the stability and aqueous solubility…
electrical properties of the chosen materials. In this work, the prepared samples are studied using various techniques given below.
• Powder X-ray diffraction(PXRD)
• Ultraviolet –Visible spectrometry(UV)
• Scanning electron microscopy(SEM)
• Energy dispersive X-ray spectroscopy(EDS)
1.8.1 Powder XRD analysis (PXRD)
The structural information of the prepared samples is examined through powder X-ray diffraction. X-ray crystallography is a tool, which is used to identify the crystal structure of…
Lab 4: Crystal Structure and X-Ray Diffraction of Materials
The purpose of this experiment is to study the relationship between the geometry of a sample and its diffraction patterns through an exploration of reciprocal space. In this experiment, both a single crystal piece of Si with a (004) reflection plane and a Si powder sample are scanned, as well as the peaks the locations of the diffraction peaks on the single crystal. The collected data is then analyzed to determine the…
liquid chromatography (FPLC) with immobilized metal ion affinity and size exclusion columns, and ultimately using the purified protein product in setting up crystallization screens. I was unable to obtain any crystals of hS100A7 due to the usage of the protease inhibitor cocktail AEBSF after cell lysis, which is known to interfere with protein crystallization. The next steps after storage of the frozen protein are to remove any endotoxins in the protein solution in order to be used in in vivo…
scanner Depends upon several steps:-
1-The x-ray tube and detector transverse (scan)
2-The radiation beam passes through the object and is attenuated. The intensity of radiation beam from x- ray tube and transmitted beam both are detected by suitable detectors.
3-The transmitted beam and the references beam are both converted into electric signals.
4-These output current signals are then converted
into digital form by analog –to-digital converter.
5-The digital data are then…
Thesis: Biomedical Engineering has enhanced medical equipment, biomechanics, and tissue engineering.
II. Medical equipment.
a. Medical imaging
iii. Robot that helps children
i. Human movement
ii. Treating injury
IV. Tissue engineering and Genetic Engineering
a- Tissue Engineering
i- The relationship between Tissue engineering and biomaterials
ii- Human tissue engineering
b- Genetic Engineering
as an MRI scan, is a type of scan that uses magnetic fields and radio wave energy to create images of the organs and tissues, such as the brain. It is a scan that is used to detect things such as tumors, infections and injuries. It is often used after an x-ray or CT scan is done to gather more information. This paper will discuss MRI in depth such as how an MRI works, its use in society, the differences between MRI and other scans and the future for MRI. …
the invention of MRIs has changed the Medical industry as medical technicians are able to produce a three-dimensional image that is non-invasive. Medical technicians put MRIs to use when trying to detect internal problems including cancers, diseases, and injures within a human body (Disher, Lenarduzzi, Lewis, & Teeuwen, 2006). Not only do medical technicians use MRIs on their patients but veterinarians also make use of MRIs on various animals to diagnose similar problems. In comparison to…
X-rays were discovered in 1895 by Wilhelm Conrad Roentgen, a Professor at Wuerzburg University in Germany. While working with a cathode-ray tube in his laboratory, Roentgen observed a fluorescent glow of crystals on a table near his tube. In the past, people were unaware of how harmful x-rays are, because they are invisible. Scientists and researchers working in the radiography field were not aware of the effect on the body after continuous exposure. When radiography was in its infancy, it was…
and x-rays is a type of electromagnetic wave. The shorter the wavelength of a wave, the more energy the wave emits. Gamma radiation has the shortest wavelength amongst all the other electromagnetic waves and has the most energy. It cannot be seen or felt and can pass through almost anything. X-rays have slightly longer wavelengths than Gamma rays and has the second most energy emission. Like Gamma, x-rays cannot be seen but unlike Gamma radiation, x-rays cannot pass through dense objects like…