Gonadotropin-releasing hormone

Introduction In vertebrates, reproduction is primarily controlled by the hypothalamus-pituitary-gonad axis. The gonadotropin-releasing hormone (GnRH) neurons in the hypothalamus are key regulators of the hypothalamic neuroendocrine system mainly though the synthesis of GnRH (Moenter et al., 2003). The decapeptide GnRH is released from the hypothalamus in a pulsatile manner, and the amplitude and frequency of these pulses change throughout the estrous cycle (McCartney et al., 2002; Moenter et al., 2003). High amplitude and low frequency pulses of GnRH secretion occur during the luteal phase of the estrous cycle with pulse frequency increasing and amplitude decreasing during the follicular phase (Savio et al., 1988; Clarke and Pompolo, 2005).…

Puberty is considered to be a period of transition consisting of both physiological and morphological changes when an individual becomes a fecund adult from a juvenile. All mammals undergo puberty (1) although the precise timing of this event is different for each species. Pubertal onset, in mammals, is governed by the pulsatile release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH promotes secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from…

synthetic decapeptide hormone which falls under the gonadotropin-releasing hormone agonist (GnRH agonist) utilized as the pamoates or acetate salts. GnRH is Triptorelin (GnRH) initiates persistent stimulation of the pituitary glands and therefore leads to a decline in the levels of follicle stimulating hormone (FSH) and gonatropins luteinizing hormone (LH) secreted by the pituitary gland. It achieves this function by over stimulating the body’s production of these hormones hence leading to a…

sources of endocrine hormones that are involved in the reproductive cycle. The three major hormones used include progesterone, prostaglandins and gonadotropin-releasing hormone (Odde, 1990). Progesterone is a hormone produced by the corpus luteum after ovulation has occurred (Odde, 1990) and its main function is to control the luteal phase (Patterson et al., 2003), prepare the endometrium of the uterus for implantation of an embryo, maintains pregnancy and reduces the amount of…

maintains blood glucose levels and other nutrients, oversees the functions of the reproductive system, controls contractions of the uterus during childbirth and stimulates breast milk, and aids in the effective of the immune system. The releasing and inhibiting hormones that are produced and released from hypothalamic neurons are the growth hormone-releasing hormone (GHRH), growth hormone-inhibiting hormone (GHIH), Thyrotropin-releasing hormone (TRH), Corticotropin-releasing hormone (CRH),…

caused when the endometrium (the growth) responds to estrogen hormone from the body, breaks down and releases blood leaving the area sored. There are a number of ways doctors use to remedy endometriosis. These are; Over-the-Counter Pain Relievers Depending on the degree of severity of the endometriosis, doctors may recommend over the counter pain relievers such as no steroidal anti-inflammatory drugs, ibuprofen…

production. Letrozole inhibits estrogen production in the hypothalamus–pituitary axis, which results in compensatory increase in gonadotropin-releasing hormone (GnRH) and FSH and stimulates ovarian follicular development. The advantage of letrozole is that it avoids peripheral antiestrogenic effects on the endometrium while stimulating monofollicular growth.9 Letrozole (2.5–5 mg daily) or anastrozole (1 mg daily) is administered for 5 days and may be accompanied by FSH (at the normal doses for…

intercourse discomfort with bowel movements lower back pain that may occur at any time during your menstrual cycle treatment Pain Medications Over-the-counter pain medications such as ibuprofen can be used, but these aren’t effective in all cases. Hormonal Therapy Taking supplemental hormones can sometimes relieve pain. This therapy helps your body to regulate the monthly changes in hormones that promote the tissue growth that occurs when you have endometriosis. Hormonal…

the variation in progression from normal to precocious puberty is a matter of concern. Beside idiopathic central precocious puberty, CAH is an important cause of gonadotropin independent precocious puberty that requires a comprehensive treatment regimen to achieve normal growth and pubertal development. Aim of the work: This study aimed to evaluate growth and pubertal changes in children with CAH. Also, to consider the idiopathic central precocious puberty. Patients and Methods: Thirty three…

I Blame the Hormones By: Taylor Aubin Organs and tissues that make up the endocrine system are the hypothalamus, pituitary gland, thyroid gland, thymus, suprarenal glands, pineal gland, parathyroid glands, heart, kidneys, adipose tissue, digestive tract, pancreas, and gonads. The effects of the endocrine system are vast and impact almost every organ and cell of the body. This system produces hormones that help maintain homeostasis through the regulation of metabolism, growth, tissue function,…