Gene

D128N Mutation in GFAP gene As it has already been studied that mutation occur at various locations on the GFAP gene, it depends on the specific point where it occurs that could result in severe consequential neurodegeneration. The mutations on the GFAP gene has already contributed for about 96% of all the cases of Alexander’s. Various other side effects that could be seen with the onset of Alexzander’s disease are GFAP aggregation, astrocyte degradation, glial injury etc. This specific…

sequence affected by it should have a role in the disease. Therefore, gene level evidence is required to establish the implication. MacArthur et al. suggested that the gene level evidence which can implicate sequence variants toward complex diseases include genetic and experimental evidence. Gene burden results are genetic evidence, and experiments addressing protein interactions, biochemical function, expression of the gene, gene disruption, model systems differences, and rescue are…

CRISPR Genes – A way to eradicate Autism to Cancer to Zellweger syndrome and everything in-between It was September 20th 2001. It was the day my mother would be screened if the fetus (i.e. me in my glorious self) showed an elevated risk for Downs Syndrome. A triple screen blood was performed which measured the quantities of three substances: Alpha-fetoprotein (AFP) which is produced by the fetus, human chorionic gonadotropin (hCG), and unconjugated estriol which is produced by the placenta. The…

A single gene can mean the difference between a normal life and a very difficult, painful, or even very short life. With technological advances in the field of genetics, such as the CRISPR-Cas9, it is now possible for geneticists to eliminate these single gene mutations that are lethal, extremely dangerous, or unbearable to the human race. Harlequin ichthyosis, cystic fibrosis and Smith-Lemli-Opitz syndrome are all caused by single genes and can potentially be edited out of the human genome.…

cluster of genes in a bacteria that are clustered together and have related functions. Genes in an operon are coexpressed, which means that they are turned on or off under a single promoter. The genes of the arabinose operon are Ara A, Ara B, and Ara D (or the B. A. D. genes) which are all digestive enzymes that allow bacteria to break down arabinose. When Ara A, Ara B, and Ara D cluster together they form the arabinose operon. The gene that replaces the arabinose operon is the pGLO gene. GFP is…

DNA and the Gene are two quite similar things. Each person contains this in their body. DNA can be found in mostly any part of the body, it could also be found in plants and other species. DNA and the gene are just part of the most important things that we have in our living system because this is what makes us look like our relatives. DNA is part of living things and if someone looks like their parent this is because they have the same Genes. Every living organism contains DNA and Genes, but…

The possible prevention of a disease or enhancing a trait is not worth potentially harming or ruining your child’s life. Around 95% of all gene therapy process results in failures, including disorders, gene mutations or even death (Bohlin). In other words, there is a less than 5% chance that the child will receive the positive, intended results. With these success rates it’s important to ask if it’s worth the chance of doing permanent damage to a child who didn’t even have a say in this process.…

eugenic policies that promoted the manipulation of their children’s genes. After viewing this film, it is difficult not to conclude that any form of gene editing technology only leads to a dystopian future in which genetic discrimination rules supreme. We must despise any potential Nazi-esque policies that Vincent Freeman had to suffer through as a result of the eugenic ideal of his society. The obvious enemy of humankind is this gene editing technology…

technology. Instead, she introduced a gene editing tool developed in 2011 by Jennifer Doudna, a graduate of Pomona College. Using proteins that precisely cut DNA, scientists can make specific genome edits, which have already resulted in cures for mice with sickle cell anemia. Almost daily, I hear about research that cures even more genetic diseases using this technique. This technology fascinates and excites me and I look forward to learning more about the impact of gene editing on our future,…

As a member of the ethnic committee, I strongly oppose gene therapy. This is because it changes human’s capability to fight against diseases. It enhances and increases human’s survival as gene therapy is used to replace disease-causing genes. As a result, humans are immune to diseases. This causes many problems to the balance of our ecosystem. One example is that this will cause human overpopulation as humans are able to overcome diseases that might cause death. As a saying goes, “One thing…