Prion

Familial Insomnia has not been given much attention directly, prion diseases in a whole have been studied by a number of different research centers. Since FFI is, in fact, a prion disease, the research being done could aid in finding a cure for patients. Research groups including, but not limited to, UCSF, MRC, Alberta, Case Western, and Rocky Mountain Labs, have spent great amounts of time to try and study the causes, effects, and cures of prion diseases. Currently, research has enlightened the…

University of Oklahoma Creutzfeldt-Jakob Disease Cody Clay HES-1823-003 Professor Joshua Carr 23 November 2015 Cody Clay Professor Joshua Carr HES-1823-003 23 November 2015 Creutzfeldt-Jakob Disease (CJD) is a rare, degenerative, inevitably fatal brain disorder that eats away at the infected person’s brain and can have many different potential causes (NINDS). There are four types of CJD; Sporadic or Classical CJD, the most common form, which occurs for a still unknown reason,…

Chronic Wasting Disease (CWD), an unusual fatal disease, is classified as a transmissible spongiform encephalopathy (Williams and Young 1980). A transmissible spongiform encephalopathy is distinguishable by a cellular protein prion to a protease isoform, which is abnormal and insoluble (Mathiason et al 2006). The disease was first seen in Colorado captive deer in 1967 (Williams and Young 1980). It is exhibited in several ungulates specifically in family Cervidae such as deer, elk (Williams 2005)…

it became viewed that there in fact was no slow virus. A new theory began developing regarding it being caused by a protein structure, known as a Prion. The theory of Prions developed around the environment of the late 1980's "'mad cow' epidemic"(Anderson 200), a bovine transmissible spongiform encephalopathy, which helped scientists discover Prions. It became understood in time, that both the mad cow…

brain. There are around 300 cases in the United States per year (NIH). CJD is also referred to as “mad cow” disease, this is because they carry the transmissible spongiform encephalopathy (TSE) (NIH). TSEs are caused by prions. In the brain, there are proteins called prions. Prions occur when a normal protein changes their shape which changes their function and are also capable of multiplying (NIH). There are two ways that CJD can be tested for. There is Electroencephalography (EEG) and…

memory loss, personality changes, and trouble with higher functioning. Emerging research shows that prion diseases and non-infectious neurodegenerative diseases may be more similar than previously thought, consequently uncovering new possible treatment routes for progressive and irreversible diseases of the brain. Diseases that are neurodegenerative, such as Alzheimer's, have a similar mechanism to prion diseases that infect the brain and slowly destroy it (Frost and Diamond, 2010). The…

were drug king pins (Race and the War on Drugs, 2007). But over the past quarter century drug arrest have tripled, and almost half a million women are behind bars for drug-related offenses (CITE), which means the women population in state and federal prions has been growing due to the War on Drugs (Cite). This paper will focus on what the war on drugs policy was about. The…

Medical Waste Regulations “Reports of medical debris keep thousands from shore,” Washington Post, July 10,1988. The poor management of medical waste resulted in the wash-up incidents on the Atlantic coast in 1987 and 1988. Following the incidents, the congress passed the Medical Waste Tracking Act of 1988. After a few years, many states responded to the wash-up crisis by formulating their own medical waste regulations. Consequently, New Jersey’s Regulated Medical Waste Management act was…

Prion has a sheet structure in place of a helical shape, as seen in a normal brain protein. Prion attacks PrP, a part of the membrane of cells which has an unclear function. When the two interact, prion alters and converts part of the PrP’s helical shape to a sheet structure, and the process is repetitive. Prion forces the body to create more of the virus, resembling crystallization (Gale 2013). Prion is similar to the enzymes related to Alzheimer's…

deer that was captive raised in Lavaca County Texas, tested positive for Chronic Wasting Disease otherwise known as CWD. This is a very contagious and fatal disease that is affecting deer, elk, and moose. CWD replicates malformed proteins known as prions that deteriorates the brain, and breaks down nerve cells. CWD kind of resembles Mad Cow Disease and can be transferred from one organism to another by blood, urine, carcasses, saliva, and even plants or soil. Since the finding of CWD has been…