Prion

Possible Modifications of Central Dogma of molecular Biology Introduction The central dogma of molecular biology is describes the transfer of genetic information within a biological system and was first stated by Francis Crick in 1956. The central dogma is the flow of genetic information as ‘’DNA makes the RNA and RNA makes the protein.’’All biological cells with few exceptions in some follow this rule. This flow takes place through three fundamental processes: replication, transcription and…

Creutzfeldt-Jakob disease affects the behaviors of people much the same way other neural degeneration diseases do, such as Alzheimer's and Huntington's. Some affected of the disease may act uncharacteristically aggressive due to themselves being frightened, humiliated, and or frustrated. The disease rapidly causes degeneration of the cerebral cortex or higher thinking portion of the brain therefore, like with Alzheimer’s, judgement and self-control will likely be affected. Good behavior and…

For the chapter 7 Nagami readings we covered a case of a slow virus attacking the brain of a patient. The virus involved was measles which the patient acquired while she was in an orphanage in India. The measles developed into a slow viral infection. In this the symptoms are masked as the patient does not appear to be suffering from the disease. The disease is replicating but it does not overwhelm the body. In this case the disease did not begin to manifest until the patient had finished her…

Chronic Wasting Disease: The Silent Assassin Chronic Wasting Disease, also known as (CWD) kills herds of deer by the hundreds. As of right now, it is a guaranteed death for any animal that contracts the disease. The Wisconsin Department of Natural Resources (DNR) started monitoring the white tail deer population in the fall of 1999. They came across there first CWD positive deer in November 2001 when they were testing harvested deer. The location where the deer was shot is unknown. (DNR.wi.gov…

Differences between Female’s & Male Prisons The statistically there are more male inmates in the United States than females. Due to these facts there are more male prisons than female prison and more services geared toward male inmates. There are key differences between male’s and female’s prisons. In United States there are about 4,500 prisons; out of the 4,500 prisons there are only around 170 female prisons. The 170 female prisons are specifically designed for female inmates; as male prisons…

“The first jails were created in England and they were called gaol” (Seiter, 2011, p.72). Early jails had terrible conditions such as filth, no medical care, and poor food. There were times when large numbers of inmates were contained in one large room. “Jails were used to house displaced persons, the poor, and the mentally ill because of the vagrancy problems during the fourteenth and eighteen centuries” (Seiter, 2011, p.72). In 1773, John Howard was the sheriff of…

cord in human that leads to patients showing neurological symptoms and death. There is currently no treatment for both diseases. BSE has a long incubation period, which makes it difficult to discover the infection at the beginning stage. Moreover, prion protein - the cause behind the disease - has high toleration. Frozen, dried, and high temperature used in pasteurisation…

(Mitrikeski 2013). Other studies have also used budding yeast to test for antibiotics; prions are one of this study. Prions are misfolded proteins that can cause neurodegeneration; in a study they used budding yeast to identify compounds that can fight these proteins by transforming budding yeast into PSI+ and URE3 and testing them. The use of the cassette ADE2 was used to replace DAL5 gene to screen for the URE3 prion, like our…

between cells, transmitting both cytosolic and membrane bound molecules, organelles and even pathogens (Marzo 2012). TNTs are implicated in transmission of prion disease by transferring in vitro endogenous PrPsc from neuronal CAD cells chronically infected with PrPsc to uninfected CAD cells, as well as exogenous, Alexa-labeled PrPsc. Prion disease transmission via TNTs is also implicated due to PrPsc transmission from mouse bone marrow-derived dendritic cells to mouse primary cerebellar…

Pencil Me In For The Zombie Apocalypse Legends of the risen dead have come from most of the world’s cultures in order to encourage fear or hope-based obedience. However, countries like England, Germany, and America have begun to use such concepts to entertain the masses through books and movies that depict the life one would experience during and after a zombie apocalypse. The zombies typically seen in movies come in three categories; zombies raised specifically to serve a master, zombies…