Muscular Dystrophy Association

Every year, thousands of people, mostly young children, are affected by the neuromuscular disease Muscular Dystrophy. There are many different types of Muscular Dystrophy and they differ based on which muscles are affected and what the causative protein in the body is. Muscular Dystrophy was first introduced to us in 1830 by Sir Charles Bell, who wrote of an illness that caused a great amount of weakness in young boys. Years later, a French neurologist by the name of Guillaume Duchenne…

first step for a diagnosis is a thorough physical examination by a doctor. Early and overall physical signs of MD will vary due to which specific dystrophy is present. The simplest early physical finding is generalized weakness that starts proximal and spreads distally. An exception is made for a few rare forms of dystrophy such as fasioscapulohumeral dystrophy (FSHD), where symptoms always start at the face accompanied by more distal weakness of extremities 4. Often the examining…

dystrophin, causes Muscular dystrophy. Dystrophin is located in the skeletal and and cardiac muscles. Alterations or mutations in the gene make it so little to know dystrophin are produced, causing Muscular Dystrophy. Without enough dystrophin muscles contract and get damaged. (2015) The mutated gene can be inherited in an X-linked pattern. This means it is passed along the X chromosome. If a mother has a faulty DMD gene, her son has a fifty percent chance of inheriting muscular dystrophy. Boys…

The protein that was concluded was dystrophin. The disease that is associated with this protein is Duchenne. Duchenne is referred to as DMD and is associated with muscular dystrophy. DMD is one of the most common gene malfunctions and is causes by having a problem with a gene which makes up the dystrophin protein. Gupta (2014) explained that when the protein is functioning properly, muscle cells are able to keep their shape and strength, but without it they can begin to break down and become…

Duchenne’s muscular dystrophy is a hereditary issue portrayed by dynamic muscle degeneration and shortcoming that happens more in males. It is one of nine sorts of solid dystrophy. DMD quality that can be acquired in families in an X-connected latent style, yet it frequently happens in individuals from families without a known family history of the condition. The quality is the second biggest quality to date, which encodes the muscle protein, dystrophin. Young men with Duchenne solid dystrophy…

Abstract: Duchenne Muscular Dystrophy (DMD) is a X-linked recessive condition in which a defective gene called dystrophin is inherited. Dystrophin is an essential protein for muscular strength and stability. DMD affects 1 out of 3600 males and the symptoms are more severe in males than in females. Symptoms of DMD include skeletal deformities, fatigue, learning and intellectual developmental delay, difficulty breathing, and heart disease. Diagnosing DMD is done through serum CPK, muscle biopsy,…

Muscular dystrophy is a group of noncommunicable diseases that is passed down through heredity lines. Noncommunicable diseases are diseases that developed in humans without other species interference and that cannot be passed between people. Muscular dystrophy can be broken up into nine major forms: Myotonic, Duchenne, Becker, Limb-girdle, Facioscapulohumeral, congenital, Oculopharyngeal, Distal, and Emery-Dreifuss. Muscular dystrophy can appear at any time in one’s life, typically in infancy or…

as DMD. Although later discovered, Edward Meryon described this genetic disease first, but by that time it had the title of “Duchenne” (Abramovitz p. 19-21). Out of nine different types (“Duchenne”), Duchenne MD, the most common of childhood muscular dystrophies (Abramovitz p. 19-21), is known as the second largest gene. Starting in the lower half of the body, over years the effects of DMD progressively move to the upper body (“Learning”). Living with the harsh effects of possibly…

Muscular Dystrophy is a disease when your muscles progressively weaken and degenerate over time. This is because abnormal genes or mutations interfere with the body’s ability to form healthy muscle tissue. There are many different types of Muscular Dystrophy. The word muscular dystrophy can be broken down into “trophe” meaning nourishment and “dys” meaning abnormal or abnormal nourishment. The first people to come in contact with Muscular dystrophy, in 1836, were Conte and Gioja. In 1852, it…

Introduction My task was replicating the experiences a seventeen-year-old male with Becker Muscular Dystrophy (BMD) could encounter. As a part of the experience, the task requires me to consider that BDM is an ailment that the principal effects are characterized by progressive muscle weakness and wasting much like Duchenne (Lister Hill National Center for Biomedical Communications, 2016). BMD is brought on by a X-linked mutations of the dystrophin gene (Mah et al., 2014). The mutation causes…