Essay On Muscular Dystrophy

Muscular Dystrophy is a disease when your muscles progressively weaken and degenerate over time. This is because abnormal genes or mutations interfere with the body’s ability to form healthy muscle tissue. There are many different types of Muscular Dystrophy. The word muscular dystrophy can be broken down into “trophe” meaning nourishment and “dys” meaning abnormal or abnormal nourishment. The first people to come in contact with Muscular dystrophy, in 1836, were Conte and Gioja. In 1852, it was reported again by Meryon. It was not till a French Neurologist named Guillaume Duchenne, that the disease got its name. He wrote about the first case in 1868, with 13 patients. He called it "paralysie musculaire pseudo-hypertrophique." Because of his work, the most severe and classic forms of muscular dystrophy are named after him.
While all cases of muscular dystrophy are similar, they all progress and continue to cause a proximal-to-distal weakness. There are 11 different types of muscular dystrophy. Duchenne muscular dystrophy is the most common among boys. Many people with this disease don’t have a family history. This is typically diagnosed when children are around two to three. Most people with this type of the disease will end up …show more content…
A defective gene related to a muscular protein called dystrophin. Dystrophin is a skeletal muscle protein. This protein is known for keeping the muscle cells intact. With the defect in the protein, it causes rapid muscular deterioration. This protein is also found in the cardiac muscles and the brain. The dystrophin gene is located on chromosome X on the short arm. It contains more than 3685 amino acids. While it only accounts for a little of the proteins, its effects are very important. Duchenne and Becker the cells dies and is invaded by macrophages. Other types are affected by complex proteins outside of the X