Heterozygote advantage

the gene. It can also be found in the French-Canadian communities in Quebec, and also the Amish community of Pennsylvania. Tay-Sachs also may have a heterozygous advantage due to the heterozygotes showing a slight protection…

Introduction Cystic fibrosis is the most frequent lethal genetic disease among Caucasians (Davis, 2006). One in every two thousand, five hundred Caucasian newborns is affected with CF, and the highest rates are among populations with ancestry in Northern Europe (Collins, 1992). Carriers can be as common as one in every twenty-five people; however, rates are typically lower within other ethnicities (Collins, 1992). Among those affected, the severity of the disease can vary. A small percentage…

When I think about Sickle Cell Anemia, the first thing that comes to my mind is blood. When you get cut and a darkish red liquid comes out, that is called blood. Blood is a red liquid that carries nutrients, gases like oxygen and carbon dioxide, and iron throughout our body. (1) Blood connects to Sickle Cell Anemia because Sickle Cell Anemia is a disease that changes the shape of our blood cells. Instead of being circle, it becomes a sickle shape. This shape can have a negative effect, but it…

Blood disorders can affect one of the four components of blood: erythrocytes (red blood cells), leukocytes (white blood cells), platelets, or plasma. The blood is affected by sickle cell diseases causing an abnormality or mutation in the hemoglobin of red blood cells. The most common type of genetic blood disorders is sickle cell diseases with sickle cell anemia being the most dangerous (Addis, 2010). Sickle cell anemia is characterized into the group of sickle cell diseases. The phenotype…

Olivia Olson Dr. Alex Hill Bio A 348 9 December 2016 Tay-Sachs: Why so Selective? There are aspects of nature that puzzle the world. Scientists, as curious as they are, try to figure out and solve nature’s great mysteries. One biological phenomenon that appears is Tay-Sachs disease. This is a disorder that tends to appear in only a handful of populations around the world. For quite sometime it was a mystery as to why this deadly disease tended to only show up in certain populations; but thanks…

Mendelian inheritance is centered around three laws discovered by Gregor Mendel. First is the law of segregation which states that during the formation of gamete the two allele pairs separate randomly. The second law is independent assortment which states during gamete formation each pair of the allele will segregate independently of the rest of the pairs of the chromosomes. The third law is the law of dominance which is that alleles can be dominant or recessive with the expression of the…

equilibrium determines gene and allele frequency ratios by using the Hardy-Weinberg equation, p^2+2pq+p^2=1. The equation can factor in evolutionary influences, for example, in some populations, people who are recessive for a particular trait have an advantage. In one case, the Sickle Cell Anemia disease “makes people who carry it resistant to malaria, a serious illness carried by mosquitos” (Learn. Genetics). Another evolutionary influence is genetic drift, genetic drift occurs when allele…

anaemia experience a shortage of red blood cells that lead to tiredness. Sickle cell anaemia, in its homozygous form can lead to a decreased life expectancy. However, in its heterozygous form, people who carry the ‘’sickle cell trait’’, are at an advantage. This is due to the increased resistance to malaria that carrying the trait provides. It is estimated that 1 in 10 people of either African or Caribbean descent are carriers. In regions where malaria is endemic, people with sickle cell anaemia…

The founder effect offers a potential explanation for the significantly higher observed heterozygosity of the Collins Creek over the pond Redbelly Dace populations. The migration of the fish to the isolated pond could have been accomplished through an anomalous transport of eggs on waterfowl or other animals travelling between the two water bodies; the small group of migrants would in turn be genetically unrepresentative of the original creek population. The disequilibrium of the Hardy-Weinberg…

biologists, physiologists, and many other scientists today, the obvious ones being their low cost, easy maintenance, ten-day generation time, and the fact that they produce large quantities of progeny. Besides these reasons, this species has more advantages for genetic analyses. While most organisms have a higher chromosome count, D. melanogaster has only four chromosome pairs, three pairs of autosomal chromosomes and one pair of sex chromosomes, making it fairly easy to determine on what…