1. Search Strategy
Search terms:
We searched those electronic databases to find relevant studies: (PubMed, EBSCO, ISI Web of Science, IBECS via Virtual Health Library, System for Information on Grey Literature in Europe (SIGLE), Google Scholar, Popline, and the New York Academy of Medicine (NYAM) through using ZIKA term .
Data title and abstract screening
After removing duplications by using Endnote software, the remaining articles were screened through abstract and title with the following criteria:
Inclusion Criteria: 1) Studies about the epidemiology, clinical manifestations, and clinical outcomes of Zika virus. (Any study reporting Information about Epidemiology of Zika including risk factors, biomarkers, prevalence, and incidence is included + studies reporting clinical signs, symptoms, and outcomes of zika infection)
2) No restriction is made with respect to study type, year, or language.
- Exclusion Criteria:
1) Animal and in-vitro studies.
2) Overlapped data sets
3) Studies that doesn't report information about the location of the patients
4) Studies in which data could not be …show more content…
-Incubation time -Clinical signs: Asymptomatic or symptomatic (Fever- Arthralgia- Myalgia- Headache- Asthenia- Abdominal pain- Edema- Lymph-adenopathy- Retro-orbital pain- Conjunctivitis- Skin Rash- back pain- anorexia- Nausea- Vomiting- Diarrhea- Constipation- Dizziness- and Other Signs )- Neurological Complication :(Guillain-Barré syndrome- microcephaly)- Underlying disease :(Diabetes- Hypertension- Asplenia- Immunodeficiency- Cirrhosis- Hyperlipidaemia- Alcoholism) – clinical outcome (Death- Microcephaly- Recovery) -Laboratory finding :CFS (Neu- Lymph- Pro- Glu) – Blood glucose – Leukopenia- Thrombocytopenia- Complet blood count(WBCs-RBCs-PL)- ESR- CRP- Blood culture- CSF culture- PCR- Liver function- Renal function- Electrolyte(Sodium- Potassium) – Bicarbonate- DIC- Interferon-gamma- Tumor necrosis factor alfa- Interleukin 6- Interleukin 8- Interleukin 12p70- Interleukin
Search terms:
We searched those electronic databases to find relevant studies: (PubMed, EBSCO, ISI Web of Science, IBECS via Virtual Health Library, System for Information on Grey Literature in Europe (SIGLE), Google Scholar, Popline, and the New York Academy of Medicine (NYAM) through using ZIKA term .
Data title and abstract screening
After removing duplications by using Endnote software, the remaining articles were screened through abstract and title with the following criteria:
Inclusion Criteria: 1) Studies about the epidemiology, clinical manifestations, and clinical outcomes of Zika virus. (Any study reporting Information about Epidemiology of Zika including risk factors, biomarkers, prevalence, and incidence is included + studies reporting clinical signs, symptoms, and outcomes of zika infection)
2) No restriction is made with respect to study type, year, or language.
- Exclusion Criteria:
1) Animal and in-vitro studies.
2) Overlapped data sets
3) Studies that doesn't report information about the location of the patients
4) Studies in which data could not be …show more content…
-Incubation time -Clinical signs: Asymptomatic or symptomatic (Fever- Arthralgia- Myalgia- Headache- Asthenia- Abdominal pain- Edema- Lymph-adenopathy- Retro-orbital pain- Conjunctivitis- Skin Rash- back pain- anorexia- Nausea- Vomiting- Diarrhea- Constipation- Dizziness- and Other Signs )- Neurological Complication :(Guillain-Barré syndrome- microcephaly)- Underlying disease :(Diabetes- Hypertension- Asplenia- Immunodeficiency- Cirrhosis- Hyperlipidaemia- Alcoholism) – clinical outcome (Death- Microcephaly- Recovery) -Laboratory finding :CFS (Neu- Lymph- Pro- Glu) – Blood glucose – Leukopenia- Thrombocytopenia- Complet blood count(WBCs-RBCs-PL)- ESR- CRP- Blood culture- CSF culture- PCR- Liver function- Renal function- Electrolyte(Sodium- Potassium) – Bicarbonate- DIC- Interferon-gamma- Tumor necrosis factor alfa- Interleukin 6- Interleukin 8- Interleukin 12p70- Interleukin