Review Questions
Write one-paragraph responses to 4 of the following 6 questions below. Each paragraph should be 5 to 10 sentences (or about 70 – 150 words), and written in your own words.
Session 1: Cell Pathology
3. Cell injury can be reversible or irreversible, and hypoxia is a major cause. Explain how hypoxia causes reversible cell injury (in particular hydropic change), which can then lead to cell death.
Lets compare a living cell to a water balloon. When we fill the balloon up with excess water, it goes into a hydropic state meaning the overall size of the balloon expands as more water is added and the lining of the balloon becomes thinner. Well to avoid the balloon from breaking, we would simply let out the excess water. When it comes to the cell, there can either be reversible or irreversible injury. With reversible injury, it is only short term, and the cell will return to its natural size once the problem is resolved. However if the problem is not corrected in time, irreversible damage will occur which will then will affect rate of cell death. When a cell receives a decrease in oxygen supply, the cell will go into a hypoxic state, which will …show more content…
When organ tissues undergo coagulative necrosis, the appearance of the organ will remain the same but the color will change. Pale appearance is due to a lack of blood supply where red appearance is due to damaged blood vessels. Liquefactgive necrosis is where tissue breaks down to a liquid form, which will have an appearance in the organ as a cystic space or an abscess. Caseous necrosis is a combination of both coagulative and liquefactive necrosis in which tissue will form a dense substance and take on the appearance as a yellowish cottage cheese. Fat necrosis will appear chalky white. Gangrene is a form of necrosis of the skin that we commonly seen where tissue appears black with or without
Write one-paragraph responses to 4 of the following 6 questions below. Each paragraph should be 5 to 10 sentences (or about 70 – 150 words), and written in your own words.
Session 1: Cell Pathology
3. Cell injury can be reversible or irreversible, and hypoxia is a major cause. Explain how hypoxia causes reversible cell injury (in particular hydropic change), which can then lead to cell death.
Lets compare a living cell to a water balloon. When we fill the balloon up with excess water, it goes into a hydropic state meaning the overall size of the balloon expands as more water is added and the lining of the balloon becomes thinner. Well to avoid the balloon from breaking, we would simply let out the excess water. When it comes to the cell, there can either be reversible or irreversible injury. With reversible injury, it is only short term, and the cell will return to its natural size once the problem is resolved. However if the problem is not corrected in time, irreversible damage will occur which will then will affect rate of cell death. When a cell receives a decrease in oxygen supply, the cell will go into a hypoxic state, which will …show more content…
When organ tissues undergo coagulative necrosis, the appearance of the organ will remain the same but the color will change. Pale appearance is due to a lack of blood supply where red appearance is due to damaged blood vessels. Liquefactgive necrosis is where tissue breaks down to a liquid form, which will have an appearance in the organ as a cystic space or an abscess. Caseous necrosis is a combination of both coagulative and liquefactive necrosis in which tissue will form a dense substance and take on the appearance as a yellowish cottage cheese. Fat necrosis will appear chalky white. Gangrene is a form of necrosis of the skin that we commonly seen where tissue appears black with or without