Acetylcholine

Alzheimer 's Disease Alzheimer’s disease is not a new disease. “Alzheimer’s” was first described by German psychiatrist and neuropathologist Alois Alzheimer in 1906. Alzheimer’s disease is an irreversible, progressive disorder involving neural degeneration in the cortex that slowly destroys the memory and thinking skills, and eventually the ability to carry out activities of daily living (Karch, 2013). In most people with Alzheimer’s, symptoms first appear in their mid-60, and accounts for…

Where is the cure for Alzheimer’s disease? The most common form of dementia is, Alzheimer’s disease (AD). Alzheimer’s can be defined as a disease that includes memory loss and inabilities that affect daily life. A common misconception is that aging comes with Alzheimer’s. Although majority people affected with this disease are 65 and above, there is also a 5% of people who are in their 40s or 50s affected by Alzheimer’s. AD is a disease of progression. There are three stages of AD and by…

Alzheimer’s Disease: A Worldwide Epidemic Charlotte Waybourn Human Disease/Pathophysiology MDCA-1302 8 April 2017 Alzheimer’s Disease: A Worldwide Epidemic Alzheimer’s is a sinister disease that can devastate an entire family and wreak havoc on the minds of the poor souls that must bear its burden. It steals their precious memories and eventually makes them a stranger to those who knew them. While there is no cure for Alzheimer’s, studies show that more women develop the disease than men,…

most typical condition which will be discussed is Alzheimer disease. Alzheimer’s disease (AD) is practically a condition where cholinergic neuron of nucleus basalis of Meynert has declined its function and affect an essential neurotransmitter; acetylcholine which is rich in…

Alzheimer 's disease is a disease in which the neurons of the brain are degenerated and deteriorated. It is progressive and slowly gets worse. It is the most common type of dementia. This disease messes with the brain 's ability to think. It also causes loss of memory, language skill, and abnormal behavioral changes. According to the Alzheimer’s Association, more than five million Americans are living with this disease, and every 67 seconds, an American develops Alzheimer 's. It is also the…

Introduction The gastrointestinal tract (GI) comprises of the oral cavity, esophagus, stomach, small intestine, large intestine, rectum, and the anus. Also, digestion process start from the mouth; the ingestion of food stimulate the salivary secretion (mouth), the food is chewed before its passage through the esophagus down to the stomach where mechanical and chemical digestion takes place. Pepsinogen from the chief cells helps with the digestion of protein, amylase from the saliva and…

In order to understand the hypothesis, first we must understand what is amyloid-beta, and how it is synthesized. Amyloid-beta is a peptide cleaved from the amyloid-beta precursor protein, which is a larger integral membrane protein found concentrated in neuronal synapsis (Masters et al., 1985;Glenner & Wong, 1984). An existing mutation in APP would lead to an increased cleavage and to a different availability of its sub products, hence increasing the amount of amyloid-beta being synthesized. A…

and interventions. In Australia, there are four drugs that are approved by the Therapeutic Goods Administration (TGA) for AD. Donepezil (Aricept), Rivastigmine (Exelon) and Galantamine (Reminyl) all work similarly by preventing the breakdown of acetylcholine in the brain, allowing for better neural function via concentration of the neurotransmitter. The outcome is a reduction in cognitive and neuropsychiatric symptoms, making early detection the key factor in maximize drug efficacy…

Have you ever thought about where dreams come from? We have all been there in the middle of the night, where a dream seems so real that you wake up thinking you have actually experienced it. Some people think dreams happen because we are recalling events that occurred earlier in the day, or maybe because we are able to have visions from the future, but do we really know their main origin? Aristotle once defined dreams as a perceptionless state where our senses of our outside stimulus are shut…

Clenbuterol is a very widely used drug and has quite a reputation. A good one among athletes and recreational users, and a very bad one among those people who know very little about illegal performance enhancing aids. Its not a steroid. In fact, the only medical use for which Clenbuterol is generally prescribed (and now being less and less prescribed thanks to its illegitimate use) is for obstructions of the air-way. People with chronic breathing disorders like asthma use this as a…