Dementia Case Study

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What is the economic impact of Alzheimers’ disease in adults in the United Kingdom and how should medicines be used to reduce that economic impact?

Dementia is an umbrella term of common syndrome where it is usually describes as brain deteriorating problem which affect memory and predominance during elderly age. In record of Alzheimer’s society (reference), one third of people who are over 65 years old will develop dementia which shows the commonness of the condition in UK. Dementia can be divided into varies categories and the most typical condition which will be discussed is Alzheimer disease. Alzheimer’s disease (AD) is practically a condition where cholinergic neuron of nucleus basalis of Meynert has declined its function and affect an essential neurotransmitter; acetylcholine which is rich in
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It can be in form of self-rated, proxy-rated, self-administered or interview administered . Generic measure such as Schedule for the Evaluation of Individual Quality of Life (SEIQoL) are less sensitive compared to disease specific measures as it is not designed to focus on a particular condition. New measurement in 2005 has been made which is Dementia Quality of Life (DEMQoL) and DEMQoL-Proxy (reference) . DEMQoL is a patient reported outcome measure which is answered by diagnosed dementia patient while DEMQoL-Proxy is answered by caregiver through an interviewer-administered questionnaires. In major studies, both of the measurement are usually take together for more reliable results. For instance, in 2011, Alzheimer’s Society has authorized a research of Qol in dementia with a report entitled ‘My name is not dementia’ (reference) which using DEMQoL and DEMQoL-Proxy with an aim to have a better view on HRQoL of less heard diagnosed dementia patients. There is also specific measurement towards AD which is Quality of Life-Alzheimer Disease

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