Alzheimer'S Disease Essay

Definition As per NINCDSADRDA criteria Alzheimer’s disease is defined as a “clinical disease caused by underlying brain changes”. Dementia is the characteristic clinical manifestation of disease. The definition of AD revolves around the assumption that an individual with an amnestic dementia would have Alzheimer’s related brain changes, namely amyloid plaques and tau neurofibrillary tangles, found at autopsy. Conversely, individuals without amnestic dementia would not found plaques or tangles…

what is the inside view of Alzheimer's patient life? Dr. Lisa Genova’s novel, Still Alice, is a monthly third-person narrative journal style writing. It is in 2003 to 2005 so that reader could see the real life aspects of Alzheimer’s from the patient’s point of view. Still Alice is the story of Dr. Alice Howland, a distinguished professor of cognitive psychology at Harvard and a reputable expert in linguistics. She finds out she has early onset Alzheimer’s disease. Even though this novel…

Alzheimer’s is a neurodegenerative disease that causes a steady decline of cognitive ability, behavioural and physical capabilities, which can be linked to characteristic pathophysiological changes in the brain. An epidemiological study have found that Alzheimer’s disease is the prominent cause of all dementia cases, accounting for more than 50% or all reported cases of dementia (Dong et al, 2012). The originating cause of this dreadful disease has been determined to be due to not just one…

Being the sixth leading cause of death in the U.S makes Alzheimer’s a common disease among older adults. Alzheimer’s is a continuous neurological disease that affects an individual’s memory, orientation and judgement. While damage begins to spread throughout the brain many abilities are lost. Cells lose the ability to perform these functions and end up making irreversible changes to the individual’s brain. Since Alzheimer’s is also a form of dementia it worsens over time. Although there are no…

due to a lack of nutrients (Alzheimer’s Disease & Dementia). Tau is the protein involved in tangles in the brain and tau aggregation inhibitors and tau vaccines are being researched for future treatment for people with Alzheimer’s. Hopefully these drugs will stop tau from forming…

the movie Away from Her. We will talk about different problems encountered in the movie, their solutions and how the movie would look like today if it was set in Las Vegas. We also hope to share our own thoughts about how we would deal with Alzheimer’s disease if we were the patient. Away from Her is a very interesting movie about a fictitious couple named Grant and Fiona Anderson. Their characters are played by Gordon Pinsent, and Julie Christie, respectively (Polly. 2006). They are a retired…

Eventually, damage reaches nerve cells that control and coordinates movement. Figure 4 Brain from normal elderly person (upper left and right)vs. brain of Alzheimer’s disease patient(Tyas 2001) The ‘Alzheimer’s Association’ related the key symptoms that individuals experience to the seven stages of AD(AD Association 2003). Progression of the disease begins with ‘No Cognitive Impairment’ stage where no memory…

Objectives and Endpoints Objective of the Alzheimer’s prevention trial was to determine if hormone replacement therapy delays Alzheimer's disease or memory loss. Achieving objective should be independent of observing a particular outcome of the trial. The outcomes of the study that can be measured objectively for determining if the intervention being studied is beneficial, are also known as endpoints. They are the quantitative measurements that are required by the objectives and are determined…

For those of you who don’t know. Alzheimer’s disease is a type of dementia; it is a progressive brain cell death that can occur in middle or old age. It affects the memory of a person. The size of the brain gradually decreases, because the amount of neurons or nerve cells and connections are decreasing. Although they cannot be seen in a living brain affected by Alzheimer’s, autopsies always show tiny inclusions in the nerve tissue, called plaques and…

When an allele increases disease risk but does not directly cause a disease, it is called a genetic risk factor. The protein Apolipoprotein E-4 is considered to be a genetic risk factor. Everyone inherits a copy of some form of APOE from each parent. Those who inherit APOE-e4 from one parent have an increased risk of Alzheimer’s. Those who inherit APOE-e4 from both parents have an even higher risk, but it’s not a certainty that they will develop the disease. It is important to point out that’s…