As stated by the Center of Disease Control, a vaccine is a product that promotes immunity therefore protecting the body from the disease and are administered through needle injections, by mouth, and by aerosol. Vaccines work by mimicking the effects of a disease or illness but not actually causing the disease or illness. The vaccine elicits a response from the body’s natural immune system; the body’s response is to fight the fight the “infection” and have natural antibodies against the pathogen if it ever were to come into contact with it again. Herd immunity is the idea that if a majority of the population is vaccinated against a disease they better it is for the entire community, vaccinated and unvaccinated alike. It reduces the amount of
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Its trade name is Ipol. It is an inactivated version of the virus so it is dead. In 1955, Jonas Salk developed the IPV and by 1961 Albert Sabin developed a live oral vaccine. The inactivated version was developed with three different strains of the virus that were grown in monkey tissues. The virus was inactivated by adding formalin. It also has IgG-mediated immunity once it is in the blood so that it does not progress and cause damage to neurons. The attenuated vaccine, also known as the oral polio vaccine (OPV), was made by the passage of the virus through non-human cells at certain temperatures to induce spontaneous mutations. There were multiple versions of the vaccine, but Sabin’s proved to be the safest and most effective. The IPV is given as an injection in the arm or the leg and is given in stages, in total there are four doses that most patients receive before they are seven years of age. The OPV is given as a single droplet that is swallowed, multiple doses are …show more content…
It is a member of the Picornaviridae family and is said to be a simple virus. It has a protein capsid that encircles the virus. The genome is a single stranded positive-sense RNA and relatively short being less than 8000 nucleotides long. It is a non-enveloped icosahedral protein coat. Poliovirus does nnot naturally affect any other species other than the human species. Mammals with the CD155 protein can be infected with the virus and the only mammals that have CD155 are humans, higher primates, and Old World monkeys. The protein contains binding sites for the
Its trade name is Ipol. It is an inactivated version of the virus so it is dead. In 1955, Jonas Salk developed the IPV and by 1961 Albert Sabin developed a live oral vaccine. The inactivated version was developed with three different strains of the virus that were grown in monkey tissues. The virus was inactivated by adding formalin. It also has IgG-mediated immunity once it is in the blood so that it does not progress and cause damage to neurons. The attenuated vaccine, also known as the oral polio vaccine (OPV), was made by the passage of the virus through non-human cells at certain temperatures to induce spontaneous mutations. There were multiple versions of the vaccine, but Sabin’s proved to be the safest and most effective. The IPV is given as an injection in the arm or the leg and is given in stages, in total there are four doses that most patients receive before they are seven years of age. The OPV is given as a single droplet that is swallowed, multiple doses are …show more content…
It is a member of the Picornaviridae family and is said to be a simple virus. It has a protein capsid that encircles the virus. The genome is a single stranded positive-sense RNA and relatively short being less than 8000 nucleotides long. It is a non-enveloped icosahedral protein coat. Poliovirus does nnot naturally affect any other species other than the human species. Mammals with the CD155 protein can be infected with the virus and the only mammals that have CD155 are humans, higher primates, and Old World monkeys. The protein contains binding sites for the