Essay Analysis Of Arti And Azemi 's ( 2012 ) Research Article

1631 Words Sep 19th, 2016 7 Pages
Analysis of Arti and Azemi’s (2012) research article, Comparing the effect of glucosamine and glucosamine with alendronate in symptomatic relieve of degenerative knee joint disease: A double-blind randomized clinical trial study, finds flaws in the study’s design, effecting the legitimacy of their recommendations. Osteoarthritis, a degenerative joint disease, comprise inflammation, degradation and narrowing of the cartilage, along with subchondral bone sclerosis in effected joints. In developed countries, osteoarthritis is a source of chronic disability in the elderly. Specifically, osteoarthritis of the knee (KOA) impacts women in Iran 2:1 compared to men, Woolf and Pfleger’s (2003) worldwide findings confirm 9.6% men and 18% women aged 60 or over being affected by osteoarthritis (Arti, & Azemi, 2012). Current treatment options for KOA involve the use of anti-inflammatory analgesics, non-steroidal anti-inflammatory drugs (NSAID’s) and glucosamine sulfates.
Arti and Azemi’s (2012) research aimed to identify and “compare the efficacy of administration of glucosamine alone and its combination with alendronate in osteoarthritis of the knee” (Arti, & Azemi, 2012, p. 87), drawing on Moroni, Faldini, Hoang-Kim, Pegreffi, and Giannini’s (2007) research into the effectiveness of alendronate use in osteoporotic bones. Intending to establish a cost effective treatment that simultaneously protects bones and cartilage, this study compared the use of glucosamine alone with…

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