Systemic inflammatory response syndrome

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    2007:30). Sepsis can be caused by pathogens other than bacteria, such as fungi, viruses, and protozoa (Munford, 2001:63). Regardless of the causative organism, sepsis can result in systemic complications that occur as circulating chemical mediators released by the inflammatory response compromised the patients cardiovascular system (Cunha, 2003:24). Severe sepsis occurs when hypoperfusion, hypotension and organ dysfunction develop. If hypotension and perfusion abnormalities, lactic acidosis, oligoria and acute onset of mental deterioration occur despite aggressive fluid resuscitation and inotropic therapy, septic shock is present (Munford,…

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    estimated 5.1% of deaths were attributed to sepsis in the United Kingdom. Consequently, it is a leading cause of admission to intensive care units (ICU), delays in hospital discharge and a significant cost to the economy. Therefore, it is imperative to raise awareness and prepare clinicians with the knowledge and guidance to embark on the global movement towards improving quality of care and outcomes for patients with severe sepsis and septic shock. Defining Sepsis: In 1991, The Society of…

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    Peroxynitrite Essay

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    It can be subdivided into 4 distinct categories according to its primary pathophysiological mechanism, namely cardiogenic, hypovolemic, obstructive and distributive (Weil and Shubin, 1971). In the first 3 types, perfusion is changed as a consequence of cardiac output decrease, whereas distributive types of shock are related to a primary dysfunction of the resistive component of the cardiovascular system. In vasoplegia, vascular tone is reduced and there is a noticeably depressed constrictive…

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    cause of admission to intensive care units (ICU), delays in hospital discharge and a significant cost to the economy. Therefore, it is imperative to raise awareness and prepare clinicians with the knowledge and guidance to embark on the global movement towards improving quality of care and outcomes for patients with severe sepsis and septic shock. Defining Sepsis: In 1991, The Society of Critical Care Medicine and The American College of Chest Physicians held a meeting with the aim of…

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    cause of admission to intensive care units (ICU), delays in hospital discharge and a significant cost to the economy. Therefore, it is imperative to raise awareness and prepare clinicians with the knowledge and guidance to embark on the global movement towards improving quality of care and outcomes for patients with severe sepsis and septic shock. Defining Sepsis: In 1991, The Society of Critical Care Medicine and The American College of Chest Physicians held a meeting with the aim of…

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    Mental Capacity Case Study

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    I let Mary know that I am going to put the oxygen mask on her as her saturation was 82% and she needed high flow oxygen. Mary didn’t reply anything but kept shaking the head while I try to put the mask on. I asked if she needed anything before I put the mask on but there wasn’t any response. I explained again why the oxygen is important and try to put it back on, which was a success at that time, but when I tried to put the blood pressure (bp) cuff on her hand, Mary took the mask off and started…

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    Kidney Injury Analysis

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    This guides providers to tailor the fluid resuscitation rate by either increasing or decreasing the infusion in response to decreased or increased urine output respectively. Urine output should be 1-2ml/kg/hr. To monitor this output, a catheter is warranted for critical care providers to quickly address changes in fluid status and prevent complications related to a deficit or an overload in fluid volume. If it is less, then either the rate should be increased or colloidal fluids should be…

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    Sepsis Research Paper

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    millions of people annually around the globe. It affects people from various divides and ages. The increase in the mortality rate among the victims of the disease has been related to the lack of knowledge among people about the disease and use of inefficient techniques in identification of the signs, symptoms and intervention SEPSIS AND WHAT I WOULD CHANGE 6 measures. Even after recuperation, sepsis survivors are still likely to suffer from other diseases due to weakened…

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    Vasoplegic Syndrome

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    Vasoplegic syndrome (VS) is a well-known form of vasodilatory shock that occurs in up to 44% of patients after cardiac surgery employing cardiopulmonary bypass (CPB)(1). CPB is often associated with a systemic inflammatory response and transient vascular dysfunction that results in profound and persistent vasodilation, leading to a decrease in systemic vascular resistance that grounds severe hypotension refractory to proper fluid resuscitation, and an increased requirement for vasopressors…

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    Sepsis is defined as the manifestation of the systemic inflammatory response to an infectious agent(Chulay&Burns, 2010). Sepsis is a complex condition that is often life threatening. It is characterized by hematological derangements and a profound inflammatory response to an infection or injury. Sepsis is a major cause of mortality and morbidity in the trauma patient. Sepsis following traumatic injury is related to the type of injury, together with the extent of injury and the anatomical…

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