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50 Cards in this Set
- Front
- Back
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epithelial cells have 3 domains |
apical lateral basal |
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Apical domain of epithelial tissue is in direct contact with __ or __ |
lumen or external enviro |
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apical is specialized for 3 things |
secreation absorp surface transport |
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microvilli on apical increaes surface area for
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absorp and secreation |
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microvili also known as |
brush border |
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microvili made of |
actin core |
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microvilli are anchored to |
actin cytoskeleton (terminal web) keeps micrvilli properly oriented |
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cilium of apical domain are used for __. they are __. |
motility they are projections of plasma membrane and cytoplasm |
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cilia made of _ in what arrangement |
microtubulues in 9 doublets + 2 singlets |
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cilium help to move _ along _ |
mucous along surface |
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4 types of intercellular jncns |
tight adherens desmosomes gap jncns |
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intercell jncns are: -sites of __ btwn cells -found in __ cells -formed by __ |
sites of adhesion found in epithelial formed by CAMs |
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Tight jncns: -found at __ -makes a __ btwn cells -CAMs adhere __ together -the more stiches, the __ |
-apical -restrictive seal -adhere the plasma membranes together -more stiches means better seal |
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tight jncns limits ____. which is __ |
paracellular flow! flow of molecs through gap btwn cells (along lateral) |
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bc of tight jncns, epithelial cells "__" what crosses epithelial barrier. __ molecs, which is __ pathway |
selects what crosses endocytoses molecs, which is TRANSCELLULAR pathway |
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so tight jncns allow epithelia to be |
selectively permeable |
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Adherens jncn: -doesnt let cells __ -CAMs are linked to __ (makes ___ e density) -found __ |
-no let cells separate -CAMs linked to actin cytoskeleton (fuzzy e density) -found below tight jncns |
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Desmosomes: -doesnt let cells _ -CAMs linked to __ via __ (are like spot welds) -found __ -look like __ |
-separate -interm filaments via disc plaques -found below adherens jncns -look like oreos |
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Gap jncns: -are for __ -pairs of cell __ molecs form __ -a gap jncn is a cluster of __ -found __ |
-molecular signalling, nutrients -adhesion molecs form transmembrane channel -gap jncn is cluster of these channels -found almost anywhere along lateral domain |
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these all make jcnal complex, which is found |
only at the apical part of lateral domain AKA TERMINAL BAR |
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Epithelium had two part classification: 1) Number of cells layers (__ or __) 2) Shape of cells in apical layer (_, _, or _) |
simple or stratified squamous cuboidal or columnar |
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in Simple, all cells __ |
contact the basal lamina ONE LAYER |
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In stratified, there are __ |
many layers of cells |
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in squamous, apical layer is |
flattened nuclei are flat |
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squamous: good for ___ Present in : |
absorbing and diffusing molecs. found in lungs and blood vessels for absorbing. |
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in cuboidal, apical layer is _. is used for |
cubed. nuclei in middle. used for absorb and secrete, but not great at either. |
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columnar look like __. nuclei are __ good for __ |
columns nuclei are at basal part good for absorb like in GI tract |
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Pseudostratified epithelium: -have dif types of cells that __ -but, all cells ___ so are actually simple! |
appear layered all cells contact the basement membrane |
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common pseudostratified cell types: -_ (w cilia) - -_ (secrete mucous) |
-columnar cells -basal cells (are at bottom usually) -goblet cells (look like goblets) |
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Stratified epithelium: -consists of _ -only the __ contacts membrane -second part of name comes frmo ___ |
-several true layers -only basal layer -comes frmo apical layer |
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basalmost layer in stratified is the __. -their job is to __ |
basal cells -job is to replenish each cell type of epithelium |
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Keratinized stratified squamous epithelium: ___ can be keratinized or non keratinized |
stratified squamous |
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Keratinized: -makes barrier that is __ and __ -keratin layer has __ and non keratin layer underneath has ___ |
tough and water resistant no nuclei has nuclei |
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Transitional epithelium: -aka __ -is a type of __ -lines lumen of __ |
urothelium stratified epithelium lumen of bladder, ureters, proximal urethra |
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Trans epithelium: -apical cells _ and _ dependign on how much __ -when distended: they _ |
-change shape and flatten depending on how much the lumen is DISTENDED WITH FLUID. -when distended, they FLATTEN |
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Metaplasia: -causes transformation of __ of __ into another type -is __ -can be caused by chronic inflamm or irritation (like smoking) |
type of mature epithelium into another type REVERSIBLE |
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the parenchyma of glands is formed by _ |
epithelial cells specialized to secrete |
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secretory compounds are stored in cell in |
secretory granules
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exocrine secretes __ into a _ or _ |
apically into a duct or a luminal surface |
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3 types o exocrine |
merocrine apocrine holocrine |
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endocrine secretes |
basally into bld vessel in STROMA |
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can tell its an endocrine gland by: |
all the e dense secretory granules on the basal side |
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secretions from endocrine glands go to |
vessels in CT |
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exocrine glands have a __ and a ___ |
secretory portion and a conducting portion (duct) |
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exocrine glands can be classified on structure of _ and _ |
ducts and secretory protein |
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ducts classifications |
simple and compound (branch or no branch) |
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secretory protein classification |
tubular and acinus (acinus is berry like) |
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exocrine can secrete serous or mucous through __ secreation (__) |
merocrine (exocytosis) |
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serous secreting glands: -lumen surrounded by __ -__ nulceus -secretory granules are __, even __, and near __ -has __ |
cell wedges ROUND nucleus dark, even e density, near apical -has basal rER |
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mucous secreting glands: -lumen with cell wedges -nucleus is __ and located at __ -secretory granules are __, even __, located at __ -has a lot lighter of stain bc mucous hard to stain except with PAS it can be light pink stain the carbs |
nucleus is flat and near BASAL foamy, even e densities, located at APICAL |
