Pernicious Anemia Research Paper

Improved Essays
Show More
Pernicious anemia is blood disease occurring rarely and defined as inefficient use of vitamin B12 and gastric intrinsic factor. Megaloblastic anemias were initially all termed pernicious anemia. Megaloblastic anemias were very fatal for those diagnosed. Pernicious translates to highly injurious or fatal because the disease was once not treatable. Megaloblastic anemias constitute any anemia that hinders DNA synthesis of red blood cells. Red blood cells require vitamin B12 for structural development. Intrinsic factor absorbs vitamin B12 within the gastric system. The root cause of pernicious anemia is believed to be an autoimmune disease of genetic inheritance (Juncà 2006). Antibodies begin to defend the body from good, healthy tissue thought to be negative, foreign invaders is a simple definition of autoimmune …show more content…
Pernicious anemia has a tendency to development other diseases in tandem with it’s own symptoms. One common dual diagnosis is atrophic gastritis, caused by antibodies defending against stomach cells that secrete digestive juices and intrinsic factor. Individuals diagnosed with atrophic gastritis typically show a current or previous infection of H. pylori. A clinical laboratory test called a Schilling test is typical for diagnosis. Vitamin B12 combined with a radioactive substance is ingested by mouth. X-rays will prove if the vitamin is being properly absorbed within the gastric system. Another more common version of diagnosis is via a complete blood count (CBC). Laboratories will draw blood from the patient and analyze the contents down to the amount of B12 present in the patients system. Symptoms of pernicious anemia are varying but commonly include asthenia, dyspepsia, jaundice, tachycardia, and angina. Long term treatment requires intramuscular injections of B12 at metered dosages

Related Documents

  • Brilliant Essays

    Anemia Annotated Bibliography
    • 246 Words
    • 1 Pages

    Anemia Annotated Bibliography

    Weatherspoon, D. (2016). Leukemia and anemia: What you need to know. Healthline. Retrieved from https://www.healthline.com/health/leukemia-and-anemia…

    • 246 Words
    • 1 Pages
    Brilliant Essays
    Read More
  • Superior Essays

    Red Blood Smear Case Study
    • 837 Words
    • 4 Pages

    Red Blood Smear Case Study

    Harold is suffering from pernicious anemia. Pernicious Anemia is caused by reduced acceptance of vitamin B12 in the body, which results in a lack of intrinsic factor that is formed by stomach mucosa. This causes Harold gastritis to damage him. “Low levels of B12 can be used to explain why fewer, but abnormally large, red blood cells can be seen on the peripheral blood smear”. Red blood cells need vitamin B12 to develop normally. This does not mean they will not grow; they just will not grow regularly as needed. The CBC results show that Harold do not have a normal number of Red blood cells , which mean the volume of the Red blood cells he produce is in elevation.…

    • 837 Words
    • 4 Pages
    Superior Essays
    Read More
  • Decent Essays

    Vitamin B1 Unit 1 Research Paper
    • 581 Words
    • 3 Pages

    Vitamin B1 Unit 1 Research Paper

    And a sufficient amount of this element in the body and lack of vitamin B12 and folic acid can give the same symptoms of anemia such as fatigue, weakness, stronger heartbeat, etc. Vitamin B12 is necessary for proper development of red blood cells and nerve cells, as a result of its continued lack develop megaloblastic anemia. Lack initially manifested by mental disorder, and then with disabilities. Insufficient amounts of this vitamin often occurs in vegans whose diet completely exclude animal products, or in the case of some diseases of the stomach and intestines that reduces the absorption of this…

    • 581 Words
    • 3 Pages
    Decent Essays
    Read More
  • Improved Essays

    Pernicious Anemia
    • 630 Words
    • 3 Pages

    Pernicious Anemia

    During this time, many doctors were trying to cure a disease call pernicious anemia. It is a disease that is caused by a deficiency. People with this disease have unnaturally yellow skin because they don’t produce enough red blood cells, prematurely gray hair, walk unsteadily, are short of breath, endure chronically swollen tongues, and suffer from numbness in their hands and feet. The new wave of research began after World War I, and doctors now took advantage of scientific method and new medical technologies. Doctors examined blood samples of anemic patients and found that they had low amounts of red blood cells. To try and fix this, they used blood transfusions. Unfortunately this only increased their red blood cell count and did nothing…

    • 630 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    Mild Iron Diagnostic Essay
    • 612 Words
    • 3 Pages

    Mild Iron Diagnostic Essay

    A. anemia has gone untreated and possibly undiagnosed. Iron deficiency anemia outset is so mild that it may go unnoticed at first. Mild iron deficiency anemia usually doesn't cause complications. But the signs and symptoms intensify as the body becomes more iron deficient and the anemia worsens. This can lead to an enlarged heart or heart failure. In addition, playing golf in a high altitude or elevation where the air pressure is reduced and oxygen levels are low do not help her condition because she already has reduced oxygen-carrying capacity due to decreased number of red blood cells (RBCs) (Gulanick & Myers, 2014). Therefore she began to experience symptoms of mild acute mountain sickness which includes light-headedness, increased heart rate and shortness of breath (MedlinePlus, 2013). Her anemia is so severe she is experiencing life threating symptoms of increase heat rate and respirations, hypotension, shortness of breath. After arriving at the hospital, her subjective data and laboratory values of decrease hemoglobin and hematocrit, normal reticulocytes, and low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) indicated that she has a type of Microcytic hypochromic anemia caused by iron…

    • 612 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    Dietetic Genealogy
    • 1091 Words
    • 5 Pages

    Dietetic Genealogy

    Canter informed readers of previous issues former dietitians faced. In the article, she discussed insulin being a great medical discovery for dietetics. Former dietitians and other healthcare professionals had to learn new vitamins and minerals that effect the action of insulin. Also these former RDs had a difficult time understanding who was at risk for insulin deficiency. Although, the problem is said to be resolved in the late 1920s, our RDs still face issues with insulin in present time. Our RDs of today still have to research the new vitamins and minerals that effect insulin. Also, understanding exactly who is at risks has been a challenge for our RDs of today's age. Other problems related to former dietetics was the treatment of pernicious anemia. Pernicious anemia is definitely a medical condition that still face problems in today's world. The main issues of pernicious anemia now and then was the treatment of the medical condition. Our dietitians of today still have to educate themselves of new findings relevant to pernicious anemia. For example, dietitians have to find foods high in B12 for patients. If certain foods do not work, then our RDs will have to research further. It compares, because formers dietitian had to first understand what vitamin B12 was. No matter of the present or past, in order to diagnosis and treat pernicious anemia you have to understand vitamin B12…

    • 1091 Words
    • 5 Pages
    Improved Essays
    Read More
  • Superior Essays

    Sickle Cell Anemia Research Paper
    • 1173 Words
    • 5 Pages

    Sickle Cell Anemia Research Paper

    Sickle Cell Anemia is an inherited blood disorder of the red blood cells, which is passed down through families. Sickle cell anemia primarily affects people with African, Mediterranean, Middle Eastern, and Indian ancestry. About 70,000 children are affected with sickle cell anemia because it directly attacks their gene, it is prevalent in African-American and millions of people carry the gene.…

    • 1173 Words
    • 5 Pages
    Superior Essays
    Read More
  • Superior Essays

    Anemia In SCD Patients
    • 1330 Words
    • 6 Pages

    Anemia In SCD Patients

    Anemia in SCD patients can be caused by problems with the spleen known as splenic sequestration crisis and aplastic crisis. In splenic sequestration crisis the red blood cells become stuck in the spleen making it enlarge rapidly. Because these cells are trapped, there are fewer cells to circulate through the blood, resulting in anemia. Aplastic crisis occurs when a common infection known as Parvovirus B19 is caught. Parvovirus is a common infection in childhood also known as fifths disease, a viral illness entailing a low-grade fever, cold-like symptoms, and a bright red rash on the face. This virus can cause the bone marrow to halt the making of red blood cells for some time which in return causes anemia. Symptoms of anemia are shortness of…

    • 1330 Words
    • 6 Pages
    Superior Essays
    Read More
  • Improved Essays

    Fanconi Anemia Research Paper
    • 1880 Words
    • 8 Pages

    Fanconi Anemia Research Paper

    Fanconi Anemia (FA) is a largely misunderstood and currently incurable genetic blood disease, affecting one out of every 131,000 births annually. Some of the disease’s early symptoms are vague and may be misdiagnosed as something as common as the flu.…

    • 1880 Words
    • 8 Pages
    Improved Essays
    Read More
  • Improved Essays

    Pernicious Anemia Research Paper
    • 631 Words
    • 3 Pages

    Pernicious Anemia Research Paper

    Pernicious anemia is a form of anemia discovered in the mid-19th century, commonly credited to the UK physician Thomas Addison for work in 1849, despite the facts that he was neither the first to describe nor name it (Lichtman et al. 563). A clinician by the name of Biermer officially named the disease, and it has been researched in depth while treated in various ways since this time. This work examines various aspects of pernicious anemia, considering fundamental traits of the disorder, mechanisms, symptoms, treatment, and other clinical work. Overall it is evident that while significant progress has been made in understanding the disease, additional work and development is required to better understand and treat it.…

    • 631 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    Hemochromatosis Research Paper
    • 693 Words
    • 3 Pages

    Hemochromatosis Research Paper

    Hereditary Hemochromatosis is an iron disorder in which the body simply loads too much iron. Too much iron can lead to life threating conditions, such as liver diseases, heart problems and diabetes. Hemochromatosis is most often seen in people who have two copies of this C282Y mutation (one from the mother and one from the father). Hemochromatosis is not something that be cured, the patient will need to be monitored and treated for the rest of his life. However, iron overload is curable. Iron is an essential nutrient found in many foods. Iron carries oxygen to all parts of the body. Normally, humans take in 8-10% of the iron in foods that they eat. People with Hemochromatosis can take in four…

    • 693 Words
    • 3 Pages
    Improved Essays
    Read More
  • Improved Essays

    Aplastic Anemia Research Paper
    • 467 Words
    • 2 Pages

    Aplastic Anemia Research Paper

    What causes anemia is your body can not make enough blood cells. Your body also destroys the red blood cells making it hard for blood to clot and cuts to heal. Red blood cells carry oxygen through out the body to different organs. There are five different common types of anemia. iron deficiency where your body doesn't have enough iron. this can be caused by menstrual cycles and blood loss. Aplastic anemia is where your body doesn't have enough bone marrow and red blood cells. vitamin deficiency this is where your body is lacking the vitamin b-12 along with iron but some people can't process b-12. Sickle cell anemia is when your blood is shaped like a sickle. The blood that is shaped like sickle will die premature. Hemolytic anemia is another anemia that involves bone marrow. The red blood cells are destroyed faster then the bone marrow can replace it. This is also what happens chemically.…

    • 467 Words
    • 2 Pages
    Improved Essays
    Read More
  • Improved Essays

    Sickle Cell Anemia Research Paper
    • 360 Words
    • 2 Pages

    Sickle Cell Anemia Research Paper

    There are prenatal tests for Sickle Cell Anemia which means they test babies before they are born with Sickle Cell Anemia. Some symptoms for it are pains in the joints, some sudden pain in the chest area. The affected child is usually treated as the symptoms occur. Doctors try to treat it by “ antibiotics, vitamins, blood transfusions, pain-relieving…

    • 360 Words
    • 2 Pages
    Improved Essays
    Read More
  • Improved Essays

    Sickle Cell Anemia Research Paper
    • 984 Words
    • 4 Pages

    Sickle Cell Anemia Research Paper

    Sickle Cell Anemia or also known as Sickle Cell Disease, is a severe hereditary form of anemia in which a mutated form of hemoglobin distorts the red blood cells into a crescent shape at low oxygen levels. When these red blood cells are affected in this way, the irregular shaped cells can get stuck in small blood vessels. If this happens, it can slow or block blood flow and oxygen to parts of the body. Symptoms of this disease easily affect people’s way of life, comfort, and overall characteristics of life. Fore example, victims of this disease have symptoms such as episodes of pain, painful swelling of hands and feet, frequent infections, delayed growth, and vision problems. This devastating disease affects 275,000 people globally, most commonly…

    • 984 Words
    • 4 Pages
    Improved Essays
    Read More
  • Superior Essays

    Common Signs And Symptoms And Risk Factors For Anemia
    • 1187 Words
    • 5 Pages
    • 4 Works Cited

    Common Signs And Symptoms And Risk Factors For Anemia

    Doctors diagnose anemia on the basis of medical histories, family histories, physical exams, and results from the test and procedures (NHLBI).Doctors may ask whether the patient had any of the common signs and symptoms of anemia or an illness or condition that could cause anemia. Patients could be asked about their current medications, diet, and family history of…

    • 1187 Words
    • 5 Pages
    • 4 Works Cited
    Superior Essays
    Read More

Related Topics

Ready To Get Started?
Discover
Company
Follow
©2023 Cram.com
Privacy Policy |  About Ads |  Site Map |  Advertise  | 
  • Cookie Settings