Mariana’s biochemistry results were requested by her GP because of suspicions she might be suffering from a liver disorder. The results showed some normalities such as the serum albumin which was within the lesser normal range of 30-50g/L. However, the level of serum bilirubin which is elevated compared to the normal range which could have been caused by a liver dysfunction. According to Thepa (2007), serum bilirubin is elevated when there is an impairment in the excretion of conjugated bilirubin from hepatocytes of bile ducts. The results also showed elevation of two of the liver’s enzymes, alanine aminotransferase (ALT) and aspartate aminotransferase (AST), these elevation could be caused by impaired liver function (Pratt et al, 2000). Mariana’s serum ALT levels is higher than the serum AST which could be caused by a form of viral hepatitis, drug or toxin induced liver injury (Limdi et al, 2003). The alterations in Mariana’s biochemistry results all seem to have been caused by a probable liver dysfunction. Fig 1: Graph showing the probability of a hepatocellular disease based on AST/ALT ratio (Kaplan, 2007).Mariana’s AT/ALT ratio is low, below 1 hinting she has viral
Mariana’s biochemistry results were requested by her GP because of suspicions she might be suffering from a liver disorder. The results showed some normalities such as the serum albumin which was within the lesser normal range of 30-50g/L. However, the level of serum bilirubin which is elevated compared to the normal range which could have been caused by a liver dysfunction. According to Thepa (2007), serum bilirubin is elevated when there is an impairment in the excretion of conjugated bilirubin from hepatocytes of bile ducts. The results also showed elevation of two of the liver’s enzymes, alanine aminotransferase (ALT) and aspartate aminotransferase (AST), these elevation could be caused by impaired liver function (Pratt et al, 2000). Mariana’s serum ALT levels is higher than the serum AST which could be caused by a form of viral hepatitis, drug or toxin induced liver injury (Limdi et al, 2003). The alterations in Mariana’s biochemistry results all seem to have been caused by a probable liver dysfunction. Fig 1: Graph showing the probability of a hepatocellular disease based on AST/ALT ratio (Kaplan, 2007).Mariana’s AT/ALT ratio is low, below 1 hinting she has viral