Philadelphia chromosome

“mongolism” before it was later termed Down syndrome in honor of his discovery. Nearly a century later, geneticists Jerome Lejeune and Patricia Jacobs reported the chromosomal abnormality for the first time in humans to be secondary to a trisomy of chromosome 21 [1]. The reason that Down syndrome is still so common today is because there has been an increase in older women having babies. Maternal age is an important factor that plays into the possibility of a child being born with Down syndrome.…

a, big B, small b will all be replicated. This will create a doubling of the DNA that existed and will later be condensed into chromosomes. After interphase, prophase I occurs; in prophase I the replicated chromosomes pair up with their homologous pairs and this creates a tetrad that is formed by the sister chromatids. The sister chromatids were the homologous chromosomes before being paired up. In reference of the last example, the replicated big A will pair up with the…

nondisjunction of the chromosomes. It usually affects the male physical and cognitive development. It is characterized by an extra X chromosome. Signs and symptoms vary for each individual. It affects different stages of physical, language, and social development. It is considered as the most common sex chromosome disorder. Etiology Klinefelter syndrome is caused by an error that results in a male to be born with an extra sex chromosome. Each cell of the human body contains 46 chromosomes, two…

forty-seventh chromosome in their cells. Though this may seem like a minimal change beyond the norm, these are the instructions for how the body should develop and if anything is thrown off balance it could result in extreme anomalies. During a process called meiosis, a type of cell division, a sperm or egg may experience a critical error called nondisjunction where the sex chromosomes do not split correctly. When nondisjunction occurs, the sperm or egg will have an extra chromosome which will…

syndrome, also known as TS and gonadal dysgenesis, is a chromosomal deficiency affecting over two million women that occur when two of the X chromosomes in a female’s DNA are either incomplete or missing entirely. It usually becomes apparent when a female is only a few years old, or even shortly following her birth. The missing genetic material of the X chromosome keeps the female body from maturing on its own. Because Turner syndrome is different for every female and an individual experience,…

Cesar Lombroso said that all criminals shared some distinctive features like huge eye sockets, enormous jaws, and handle shaped ears. This theory forms part of an old debate of nature versus nurture that still continues in today’s days. Francis Galton’s field basis, “eugenics”, was that inheritance is more important than the environment and education. For him “talent, character, intellect, disposition, and other aspects of "natural ability," as well as physical features, such as height and eye…

Y chromosome is a sex determine chromosome among many species including modern humans. Modern studies in genome suggested that Y chromosome arose from the accumulations of mutations of other chromosomes and have some special genes on it which determine the gender of the carrier; however, some non-mammalian animals carry the Y chromosome even if their genders are not determine by the appearance of the Y chromosome. The Y chromosome works differently on the mammalian and non-mammalian so in this…

without Turner syndrome, they have two sex chromosomes. For males, that would be one X chromosome and one Y chromosome. For females, they would have two X chromosomes. For females who have Turner syndrome, they have one normal X chromosome and the other is either missing or structurally altered. The chromosomal abnormality occurs as a random event during the formation of reproductive cells in the affected person’s parent. When a pair of chromosomes fails to separate during the formation of…

Lesson 2: Assignment 1-Genetic Information Resources, Assignment 2- Critical Thinking Exercise, and Assignment 3-Definition Matrix Tabytha Balash Ohio University  Assignment 1: Genetic Information Resources There are several areas to retrieve information on genetics. The following paragraphs will summarize three organizations that provide information on genetics, genetic counseling, and genetic testing. The summary will include what information is obtainable from the site, who supports the…

The concept of the Ronald McDonald House Charity was shaped through the help of the NFL Philadelphia Eagles team, and proceeds from a local McDonald’s back in 1974. The partnership was formed after the former Eagles tight end, Fred Hill, daughter was diagnosed with Leukemia. Hill and his wife never left their daughter's side during her treatment. Hill began to see the struggles that himself and other families are faced when a loved one is sick. With hours of checkups and treatments, families…