Orphan drug

Orphan drugs under normal market circumstances would not be produced by the pharmaceutical companies due to the expense incurred and potentiality of financial loss due to low levels of sales. Orphan drugs are created to treat, prevent, and diagnose rare diseases with a prevalence of less than 5 in 10,000 per community. An Orphan medicinal product must show an enhanced therapeutic benefit over existing treatments against rare life threatening or debilitating diseases. An orphan drug is not a rare drug but a rare disease and the drug can be an old drug if you like but can a new drug also. At the moment there are a plethora of old drugs without the advent of a patent to shield it from competitors. The terminology in the US to describe drugs which treat rare diseases is known as Orphan drugs whereas in the EU these drugs are coined rare disease…

blanket on the bed. I wish someone could adopt me so I wouldn 't be living this hell. Being alone wasn 't fun, and I would do anything to not be alone. I sighed in frustration. I climbed in my bed laying my head on the soft pillow and covering myself with the blanket. Getting ready to relax, but before I could a loud explosion was heard from the other side of the orphanage. I jumped out the bed and darted out the girl 's dorm rooms. Smoke clouded the hallways making it hard to see, but I still…

orphanages at an early age, specifically from newborn to the developmental years of two years old, are at a very high risk of having many early developmental complications. An orphanage is defined as the housing and care for orphans where they are to be fed and cared for, however despite the orphans receiving their basic needs, many children are still lacking the experience-expectant skills that they desperately need as they continue to grow. This is an extreme concern not only for our youth,…

One day when George and Mary were ready for supper and the table was set without any food, they still prayed to God. But then people from the church came to them with a whole entire ham and said: "I cannot eat supper because I know you two are starving." One day, George decided to build an orphanage, everyone thought that it cannot be possible because he had no idea where to build, and how many orphans, and how old. He didn’t even have money, which is most important thing in…

Cold and dreary. This is the feeling that Ava Perkins woke up to every morning. She dreadfully got out of bed and put on her rusty slippers that were immersed in dirt. Everything Ava received was handed down to her from the other children of the orphanage. Ava's parents had left her when she was two months old. Ava always wondered why her parents didn't want her, and where could they be? Ava's daily ritual was to gaze out her shared rooms tiny window, and think about her future aspirations. Ava…

The orphan children are not white not white, male, nor property owners and are excluded from that privilege of life. Non- citizenship theory concept applies directly to them before the government got involved, they were ignored, pushed around, and abused. Which leads to being denied their social citizenship which is the rights to social services, like shelter opportunities, food or clothing availability. But once the government gets involved they turn into second class citizenship since it was…

I believe there are two types of people. Those who question nothing, and those who question everything. For better or for worse, I reside in the second group. Although there are countless questions swimming around in my head, and innumerable problems I wish to solve, the one that holds the most precedence is this; The condition of orphans throughout the globe. This past summer I had the amazing opportunity to help in several orphanages in Niger, Africa. Not only did this experience completely…

The main characters in Orphan Train are Molly, Vivian, and Dutchy. Molly is a seventeen year old girl who is in and out of Orphan homes due to her dead father and mother who turned to drugs. She battle with jarring foster parents and siblings.She is hopeful to find someone who will love and accept her for who she is. Vivian is a ninety-one year old woman who Molly did some community service for. Although through time, Vivian and Molly created a heartwarming bond like no other. The final main…

Problems, which are socially constructed, are conditions that are perceived as solvable whereas conditions are external events that we encounter in our everyday lives. It is important for political actors to correctly identify problems and their causes so that the existing understandings of an issue can be challenged. For instance in the Medicare Catastrophic Coverage case, gaps in Medicare coverage left elderly Americans vulnerable to catastrophic illness. However, political actors realized…

Orphan Train, by Christina Baker Kline, tells the story of two very different aged orphans, Vivian and Molly, who come together through their similar adolescence experiences and work to overcome their fear of loss and trusting others. The novel starts off with a troubled teen, Molly, who got caught stealing a book from the library. She is given the opportunity to do community service by helping an elderly woman named Vivian clean out her attic. Molly gladly accepts to prevent having to go to…