Myelodysplastic syndrome

Myelodysplastic syndromes, also known as MDS and pre-leukemia, are a group of disorders caused when the production of white blood cells, red blood cells, or platelets is interrupted (Myelodysplastic Syndrome Treatment 2016). These syndromes are rare, fewer than 14,000 cases of myelodysplastic syndromes occur in the United States each year (Statistics about Myelodysplastic syndromes). Blood cells and bone marrow do not fully develop or become mature enough to function properly when a person has myelodysplastic syndromes. Blood cells not becoming mature can cause many problems. If the white blood cells, the blood cells that fight infection, do not work properly infections will be more prevalent. The body of the patient will not be able to fight…

Sung Noh 12/11/2014 BSCI 330 Hypermethylation in patients with Myelodysplastic Syndrome Myelodysplastic Syndrome is disease of the bone marrow in which its ability to produce viable blood cells has been compromised through mutation. In healthy bone marrow the Osteocytes that live within produce hematopoietic stem cells that mature to become different components of blood: erythrocytes, neutrophils, monocytes and platelets (Saba et. al, 2007). Osteocytes that have undergone mutations produce a…

Myelodysplastic Syndrome Myelodysplastic syndrome (MDS) is a group of blood diseases that affects new blood cells. This syndrome starts in the bone marrow where new blood cells are made. New blood cells are called immature cells or stem cells. With MDS, some immature cells do not grow into adult blood cells. Immature blood cells cannot live for very long in the body and they die. Over time, immature blood cells crowd out normal adult blood cells. This causes a low blood count. The bone marrow…

This is a test to screen a pregnancy to determine whether a baby has an increased chance of having specific chromosome disorders. The test examines the baby's DNA in the mother's blood. Williams Syndrome Williams syndrome is a rare disorder that can lead to problems with development. It is passed down in the offsprings of families. One of the 25 missing genes is the one that produces elastin, a protein that allows blood vessels and other tissues in the body to stretch. It is likely that…

Mohammad Ekrama Biology 22 Professor Clark 1october 2016 Christianson Syndrome Abstract: Christianson Syndrome is a super rare disease, it is a recessive X-linked disorder ,that usually affects the human body, specifically the nervous system. There are a lot of symptoms for this disorder like ataxia, seizures, epilepsy, severe mental retardation and microcephaly. Mutations on the SLC9A6 gene cause Christianson Syndrome, this gene is located on the X chromosome. This disorder is usually…

disabilities, what sickle cell does in children with neurodevelopment disorders, and what psychiatric disorders and down syndrome does in adolescents and young adults. This paper will only contain abstracts of my own doings for each journal I have obtained for this study. I will not be going into depth with every single disorder that is within a neurodevelopment disorder such as Mendelsohn’s Syndrome or…

Angelman syndrome is a rare genetic disorder that affects around 1 in around 12,000-20,000 live births and affects both males and females equally. Angelman syndrome is very often misdiagnosed as autism or cerebral palsy. Angelman syndrome is not an inherited disease, and is instead caused by a change in the E3 ubiquitin protein ligase gene (UBE3A) on the maternal chromosome 15. This change prevents the chromosome from functioning properly. It occurs as a random event during the formation of eggs…

Overview: What is Williams Syndrome? Definition: Williams Syndrome is a genetic disorder, resulting from the deletion of 26 or more genes one chromosome number 7 (Mervis et al., 2000). That seemingly small loss can affect numerous parts of a person’s physical and mental health, as well as social behavior and sensory perception (Genetics Home Reference, 2014). Diagnosis: Williams Syndrome is a genetic condition that a child is born with and it can impact a child’s prenatal development as well…

In 1965 Harry Angelman reported clinical findings in three children with similar, unusual, attributes. These children had what was known as “happy puppet” syndrome, but was later changed to Angelman syndrome, due to its pejorative name. Angelman syndrome is a neurodevelopmental disorder distinguished by: severe learning difficulties, ataxia, jerky movements, epilepsy, speech impairments, hypopigmentation in the hair and the skin with blue eyes, subtle dysmorphic facial features, and happy and…

The speaker Adrienne Bashista gave a very insightful speech about what Fetal Alcohol Syndrome is and how it is caused. Before our speaker told us about her son, I had very little knowledge about what FASD was. I now realize how severe FASD is and how even the slightest consumption of alcohol can affect a fetus during pregnancy. I became aware that FASD is a rare syndrome that only 2 to 5 percent of the population have. This statistic surprised me due to a large amount of woman who may drink when…