Disease-modifying antirheumatic drug

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    Crohns: A Case Study

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    S feels some the side effects from medications are just as bad at the symptoms of Crohns. For example Humira (adalimumab) is a class of drug called disease-modifying antirheumatic drugs (DMARDs), an immunosuppressive drugs that interfere with natural immune function to reduce the inflammation in his colon (Burchum & Rosenthal, 2016). These types of medications increase the risk of infection and cancer (Burchum & Rosenthal, 2016). After taking Methotrexate (another DMARD), S developed lungs problems. S has experienced three different pneumonia infections, sever pain at the injection site, decreased lung function and chronic fatigue. His SOB developed so severely that he failed his stress test. His is now taking respiratory inhalers to help with his…

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    swelling, bone erosions and redness in hand and feet. How would you act in response? You wouldn’t be to understand when someone is dealing with Rheumatoid Arthritis (RA) that frequently establishes itself in several joints in the body. Affecting two or three times more women than men. It can be generic .There are no cure for this chronic disease, but many aggressive treatments and medicines can help to prevent deformity of the joints. The rheumatoid arthritis (RA) is an autoimmune system that…

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    An autoimmune disease develops when your immune system decides your healthy cells are foreign. As a result, your immune system attacks healthy cells. Depending on the type of autoimmune disease you have, it can affect one or many different types of your body tissue which can cause abnormal organ growth and changes in organ function. There are as many as 80 types of autoimmune diseases. Many of them have similar symptoms, which makes them very difficult to diagnose. It’s also possible to have…

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    Palindromic Rheumatism Palindromic rheumatism is a condition in which there are episodes of pain, swelling, warmth, and stiffness in the joints. The episodes are unpredictable and can last from hours to weeks. Episodes can happen weeks to months apart. In about half of people who have this condition, episodes happen more and more often with time. These people are at risk for developing rheumatoid arthritis, a disease that causes pain, swelling, and stiffness in the joints. CAUSES The cause of…

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    Rheumatoid Arthritis is an autoimmune disease that targets synovial tissues, cartilage and bone (Smolen & Keystone, 2012). In an autoimmune disease, the immune system mistakes the body's own cells for invaders and attacks healthy cells and organs instead of pathogens (Spriggs, 2014). The two long bones of the forearm, the radius and the ulna, are connected through the radioulnar joint, a joint that is divided into a proximal and a distal half (Savvidou, Murphy, Mailhot, Shushan, Scheker, 2013).…

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    Introduction: Rheumatoid arthritis (RA) is an autoimmune disease that is for a long term. And it’s happen in the joints, surrounding tissue and other organs causing inflammation of those organs. Causes: The cause of RA is unknown and not clear. It is an autoimmune disease which means that the body attacks by mistake their own immune system and the healthy cells. But it's thought it may involve environmental factors, genetic makeup and hormones changes. Smoking may involve to RA. It happens…

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    there to understand when someone is dealing with the symptoms of Rheumatoid arthritis RA is a chronic long live disease that can cause disability and decrease the quality of live. In which the body immune system exterminated its own connective tissue. This disease is to make distinctive by inflammation in the synovium the tissue that lines the joint. When the synovium is attacked, it becomes damaged. Eventually, the joint cartilage possibly begins to deteriorate. This lead to destruction of the…

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    Methotrexate Case Study

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    Methotrexate, used as the first-choice disease-modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA) and in some cancer chemotherapy regimens, acts by inhibiting dihydrofolate reductase, which results in a relative deficiency of bioavailable folate. Its action as an anti-inflammatory is less clear. The abnormal synthesis of tetrahydrofolate interferes with thymidine metabolism and DNA synthesis. This leads to the nuclear-cytoplasmic maturation dissociation of the megaloblastic…

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    Rheumatoid arthritis is disease, which is chronic in nature and causes severe inflammatory disorder that can affect more than the joints. It has the potential to damage essential components of our body like skin, eyes, lungs, heart and blood vessels. It is a situation, which happens when the immune system of one’s body starts attacking its own tissues. The rheumatoid arthritis is a bit different from osteoarthritis in the fact it starts impacting the lining of one’s joints along with a…

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    systemic disease marked by inflammation of multiple synovial joints.” The inflammation within the articulations causes the synovial fluid inside the joints to harden making range of motion decrease significantly. Over time, if left unmonitored, the cartilage between the joints breaks down, causing permanent joint damage and deformity. There are an estimated 2 million people in the United States afflicted by rheumatoid arthritis with approximately 75% of those people being female. The…

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