Disease-modifying antirheumatic drug

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  • Crohns: A Case Study

    S feels some the side effects from medications are just as bad at the symptoms of Crohns. For example Humira (adalimumab) is a class of drug called disease-modifying antirheumatic drugs (DMARDs), an immunosuppressive drugs that interfere with natural immune function to reduce the inflammation in his colon (Burchum & Rosenthal, 2016). These types of medications increase the risk of infection and cancer (Burchum & Rosenthal, 2016). After taking Methotrexate (another DMARD), S developed lungs problems. S has experienced three different pneumonia infections, sever pain at the injection site, decreased lung function and chronic fatigue. His SOB developed so severely that he failed his stress test. His is now taking respiratory inhalers to help with his…

    Words: 1354 - Pages: 6
  • Methotrexate Case Study

    Methotrexate, used as the first-choice disease-modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA) and in some cancer chemotherapy regimens, acts by inhibiting dihydrofolate reductase, which results in a relative deficiency of bioavailable folate. Its action as an anti-inflammatory is less clear. The abnormal synthesis of tetrahydrofolate interferes with thymidine metabolism and DNA synthesis. This leads to the nuclear-cytoplasmic maturation dissociation of the megaloblastic…

    Words: 494 - Pages: 2
  • Assignment On Clinical Pathology

    write your name on the assignment text and article. Assignment and rubric: Choose a disease, syndrome, or other pathology that has relevance to the practice of Physical Therapy to cover for this assignment. You can choose one from the book or journal article or from a class presentation – as long as it was not something that was discussed in depth in Tegrity or in-class lecture. Answer the following questions as concisely as possible. I am not looking for a long paper here, just include the…

    Words: 1900 - Pages: 8
  • Methotrexate Research Paper

    Methotrexate is a drug used to treat cancer, psoriasis, rheumatoid arthritis, lupus, and to induce miscarriage in women who have had ectopic pregnancies. Question 1: Pharmacokinetics describes how the body affects a certain type of drug after administration through absorption, metabolism, distribution and excretion while travelling throughout the body. Absorption Absorption is defined as the movement of a drug through the bloodstream. Absorption of a drug is affected by the solubility of the…

    Words: 1438 - Pages: 6
  • Causes Of Autoimmune Diseases

    Autoimmune diseases affect about 50 million of the American population according to the American Autoimmune Statistics. Autoimmune occurs when the immune system can not detect the difference between self and nonself. The human immune system protects the body from foreign virus’ and sends antibodies to kill the unknown virus or intruders. This disease then causes the body to produce antibodies that will attack against the body’s healthy cells. It proceeds to attack itself and it’s healthy body…

    Words: 2562 - Pages: 11
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