The Pros And Cons Of Animal Models

Often, when in experimentation, animal models are used in order to predict what would happen in human.Animal models have helped us our understanding of mechanisms of disease ( Worp, Howells, Sena, Porritt, Rewell,O’collins & Macleod 2010). In certain area, animal models’ use is controversial for example, when it come to predicting the effectiveness of treatment strategies in clinical trials; while the animal models are often promising, it failed to translate that promising result when it comes to trials ( Worp & al 2010). When it come to food experiments, animal model especially rodents have its use, however, it does have its limitations. After all, we are not genetically the same. Recently in 2011, the use of chimpanzee in animal models have been deemed unnecessary and chimpanzee is closest to humans at 98% .
Food is a major subject today, especially in the face obesity. …show more content…
Its global incidence is still risen and drives the rate of morbidity and death related to cardiovascular and cerebrovascular diseases quite high ( Vickers, Jackson & Cheetham 2011).Ever so often, we see an article about the current ingredients in the food that fast food restaurants like Mcdonald’s serve and how unhealthy they are. So far, animal models seem to be helpful in understanding certain aspects of obesity in animals, and more importantly humans. They have been used to discover novel treatments for obesity in different aspects. They have been used to measure food intake in lean rodents and in long term studies in animals that shows signs of obesity; They can be use to determine factors about weight loss and evident changes when it comes to obesity (Vickers, Jackson & Cheetham 2011). Therefore, it is quite possible to use animal models in a food related aspects.Furthermore, behavioural models such as the behavioural satiety sequence can be used to confirm that a drug treatment has a selective effect on food intake; the predictive value of animal models when it comes