It is physically alike and can be altered to react the same as human skin as well. According to Mertsching, et al, “Reconstructed human skin equivalents are the models that most closely mimic nor- mal human skin. They allow the topical application and skin irritancy testing of a great variety of products used in daily life” (Mertisching, et al. 1). The 3-D skin is made from human keratinocytes which is an epidermal cell in natural skin. It grows and acts like human skin so it makes a great alternative to using animal skin to test for skin sensitization and toxicity
It is physically alike and can be altered to react the same as human skin as well. According to Mertsching, et al, “Reconstructed human skin equivalents are the models that most closely mimic nor- mal human skin. They allow the topical application and skin irritancy testing of a great variety of products used in daily life” (Mertisching, et al. 1). The 3-D skin is made from human keratinocytes which is an epidermal cell in natural skin. It grows and acts like human skin so it makes a great alternative to using animal skin to test for skin sensitization and toxicity