Sickle Cell Anemia ( Red Blood Cells Essays

1039 Words Oct 6th, 2014 5 Pages
Blood disorders can affect one of the four components of blood: erythrocytes (red blood cells), leukocytes (white blood cells), platelets, or plasma. The blood is affected by sickle cell diseases causing an abnormality or mutation in the hemoglobin of red blood cells. The most common type of genetic blood disorders is sickle cell diseases with sickle cell anemia being the most dangerous (Addis, 2010). Sickle cell anemia is characterized into the group of sickle cell diseases. The phenotype number for sickle cell anemia is #603903 on the HBB gene/ locus (OMIM, 2014). Sickle cell anemia can also be known as HbS disease, hemoglobin S disease, and hemoglobin SS disease (NHLBI, 2012). Sickle cell anemia is identified by both its description and inheritance patterns.
The red blood cells of the population that inherits the trait lose their shape and become sickled when the oxygen levels in the blood change. The change in shape causes the red blood cells to be destroyed when they clump together. This gives the blood cells a shorter life span of less than twenty days. The normal red blood cell has a life span of about one hundred and twenty days. When the oxygen levels are lowered, the cells go into sickle cell crisis and the end result could lead to fatality. The pain associated with the symptoms of sickle cell anemia is called sickle cell crisis (Tchuenche, 2005). Sickle cell crisis can also be called vaso-occlusion. Vaso-occlusion occurs when an individual is exposed to physical…

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