Genetic Comparison Between Sickle Cell Anemia And

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A mutation is any change in the DNA sequence. Sometimes a base is deleted or extra bases are added. Most common is a point mutation, where a single base is substituted for another, but some of these occur in the non-coding sequences and become a silent mutation. When a DNA change remains unrepaired in a cell, it is passed down to the offspring. However, most mutations result in recessive genes. Because humans are diploid, meaning that the individual has two sets of chromosomes from each parent, they are less likely to occur, acting as a safeguard against mutations. The offspring needs two mutated copies in order to have mutation, which is why they appear in the recessive gene more often than the homozygous dominant and heterozygous. This is the case with Sickle Cell Anemia, where there is an amino acid substitution, which changes the shape of the protein, causing the cell to sickle. …show more content…
This is a disease in which the hemoglobin protein is produced incorrectly and the red blood cells have a sickle shape. A person that is homozygous recessive for the sickle cell trait will have sickled red blood cells that all have the incorrect hemoglobin. A person who is homozygous dominant will have normal red blood cells. From the images on the first page in the packet, this trait is an example of incomplete dominance, as a person who is heterozygous for the sickle cell trait will have some misshapen cells and some normal cells. From the results, this was the case for the

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