Central Nervous System Essay example

1492 Words Mar 18th, 2016 6 Pages
Psychiatric disorders, such as Schizophrenia, mood disorders, and addiction, represent complex diseases of the brain, which are subsequently associated with numerous patterns of clinical symptoms (Peled, 2008). The general idea that the brain is the responsible for generating and maintaining mental function, has spurred modern psychiatric efforts to determine biological mechanisms implicated in mental illness (Montague et al., 2012). However, the sheer complexity of such approaches becomes quite evident when considering the makeup of central nervous system (CNS) which is estimated to comprise 1011 neurons, where each neuron receives and delivers 104 inputs and outputs respectively (Gould and Manji, 2004). As a consequence, the dominant and prevailing ideology in neurobiology is that of reductionism, in which several sub categories are included such as molecular-, genetic- and environmental reductionism (Rose, 1973). Although, such efforts have been successful in driving the development of several generations of clinical anti-depressant, anti-anxiety and anti-psychotic drugs, there is still an enormous explanatory gap between neuroscience and biological psychiatry in terms of intermediate levels of description relating molecular level concepts to clinical level concepts (Montague et al., 2012).

Neuropsychiatric disorders, are highly prevalent and frequently manifests in early life, thus substantially contributing to the worldwide disease burden (Nestler and Hyman, 2010).…

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