Systemic Lupus Disease Case Studies

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INTRODUCTION Systemic Lupus Erythematosus (SLE) is an auto-immune system. Auto mean self. Autoimmune means that our immune system cannot differentiate between foreign invaders and our own healthy body tissues and decide that our healthy cells are foreign substance. Thus, creating autoantibodies which are protein that attack and eventually destroy the healthy tissues. This means that our body ability to prevent and fight against infection are reducing. SLE is more than any connective tissues disease, it is more to multisystem disorder. The cause of SLE is still unknown. There are no cure for this disease, but there are always prevention steps. Around 3% of the population has this autoimmune disease. There are striking sex differences in this …show more content…
Epidemiology is a study of determinant of health relater state or events in a specific population and the application to control the problems. The lupus disease has been analyzed for some period of time. One of the epidemiology is age. The peak age among women seems to be during childbearing years, between 15 and 40 years. A community survey in Birmingham (United Kingdom) there are reports on SLE in women ages 18 to 65 years, 54 per 100,000 people were diagnosed and increased to 200 per 100,000 people diagnosed with SLE. (Johnson, Gordon, Hobbs, & Bacon, 1996). The strongest risk factor are obviously the gender. SLE is more frequent among women than men.
Other than that, SLE has been found worldwide and most commonly found in some country which were describe in Europe, North America, South America, Africa, Asia, and Australia. (Guillermo J. Pons-Estel, 2008) .The population of diagnosed people with SLE in Africa and Asia background are approximately 2 to 3 times higher compared to the white population. SLE are actually low in children compared to adult rate. In Taiwan, SLE among children was estimate as 6.3 per 100,000. (Huang JL, 2004). Genetic factor also play important role as the disease can be
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These two are important components of the immune system that play a role in the inflammation. Both of the cells belong to the immune cell’s family called lymphocytes. In human body, lymphocytes help to fight infection. Antigens are foreign substances such as bacteria and viruses that stimulate the immune systems to produced autoantibodies. When a T cell recognized antigens in body, it will produce cytokines that will cause B cells to multiply in number and release protein called antibodies. This antibodies will travel and circulate widely in the bloodstream of human bodies, recognizing the foreign particles and trigger inflammation to get rid the

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